Earticle

초록

영어

This study investigated the effects of Gymnema sylvestre (GS) extract on body weight, adiposity, and lipid metabolism in leptin-deficient ob/ob mice. The experimental mice were divided into the following 4 groups: basal diet (AIN-93G diet) and 0.5%, 1%, and 1.5% GS supplemented groups. Each group was fed the experimental diet for 9 weeks. The final body weights, adipocyte sizes, and epididymal fat weights of the GS groups were significantly lower than those of the control group. There were no significant differences in food intake and food efficiency ratios among the treated groups. Serum triglyceride levels and the atherogenic index were significantly lower in the GS groups compared to the control group. Serum HDL cholesterol levels were significantly higher in the 1% and 1.5% GS groups compared to the control group. Serum glutamate oxaloacetate transaminase and glutamate pyruvate transaminase activities did not differ among the four experimental groups. The total hepatic lipid content was significantly lower in the GS groups, and hepatic cholesterol and triglyceride contents tended to be reduced in the GS groups compared to the control group. These results suggest that GS extract may be useful for ameliorating dyslipidemia and fatty liver

목차

Abstract
 서론
 재료 및 방법
  실험동물의 사육 및 식이
  혈청 분석
  간조직 중 자질 함량 측정
  지방조직의 형태학적 변화
  통계처리
 결과 및 고찰
  혈청 GOT/GPT 활성
  식이섭취량 및 체중증가량
  지방조직의 무게와 조직 변화
  혈청 내 지질 및 혈당 수준
  간 내 지질 수준과 조직변화
 요약 및 결론
 문헌

키워드

저자

• 엄민영 [ Min-Young Um | 한국식품연구원 ]
• 안지윤 [ Ji-Yun Ahn | 한국식품연구원 ]
• 김성란 [ Sung-Ran Kim | 한국식품연구원 ]
• 최상윤 [ Sang-Yoon Choi | 한국식품연구원 ]
• 김경진 [ Kyung-Jin Kim | CJ 주식회사 ]
• 김세곤 [ Se-Kon Kim | CJ 주식회사 ]
• 이진희 [ Jin-Hee Lee | CJ 주식회사 ]
• 김성수 [ Sung-Soo Kim | 한국식품연구원 ]
• 하태열 [ Tae-Youl Ha | 한국식품연구원 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국식품과학회지 [Korean Journal of Food Science and Technology]

• 간기

  격월간

• pISSN

  0367-6293

• 수록기간

  1969~2011

• 십진분류

  KDC 574 DDC 664