The effects of dietary supplementation of the unrefined rice bran oil from 'Suwon 415' pigmented black rice (BRBO) on cholesterol metabolism and cellular antioxidant status were investigated in hypercholesterolemic rats. The significant reduction of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) concentrations was observed in the plasma of rats fed BRBO. BRBO also decreased plasma and hepatic oxidative stress as a result of increased levels of hepatic thiobarbituric acid reactive substances (TBARS) levels associated with the elevations of hepatic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities together with increased plasma level of tocopherol. This study indicates that dietary BRBO supplement can leads to the improvement of overall cholesterol metabolism and antioxidant status even more effectively than 'Chuchung' white rice (WRBO). Consumption of BRBO may also protect the liver from oxidative damage caused by lipid peroxidation.
목차
Abstract Introduction Materials and Methods Rices and rice bran oil Animals and diets Tissue preparation Measurment of plasma and hepatic lipids Measurement of plasma and hepatic lipid peroxides Measurement of plasma vitamin A and E contents Determlnation of antioxidant enzyme activities Statistical analysis Results and Discussion Food intakes, body weight, and organ weight Plasma and hepatic lipids composition Plasma and hepatic lipid peroxides Plasma and hepatic antioxidant status References
키워드
rice bran oilpigmented black ricehypercholesterolemic actionantioxidant statuslipid peroxidation
저자
Yean Ju Nam [ Department of Food Science and Nutrition Kyungpook National University ]
Corresponding author
Seok Hyun Nam [ Department of Biological Science, Ajou University ]
Mi Young Kang [ Department of Food Science and Nutrition Kyungpook National University ]