Abstract Introduction A New screening Method for δ-Endotoxins fo B. thuringiensis Formation of the biosensor simulated a brush border membrane Interation between δ-endotoxin and BBM by the SPR-based system Comparison the methods for interaction of Cry toxins with the receptors Identification and Characterizatio of Parasporin-7 Indentification of two cytotoxic proteins of the B. thuringlensis A1470 strain Morphological changes in cultured cells by the recombinant parasporin-4 protein Cytotoxic activity of parasporin-4 against various mammalian cells An Efficient Preparation Method for Parasporin-4 Solubility of the recombinant pro-parasporin-4 in various solutioins Cytotoxic activity of the recombinant parasporin-4 processed by pepsin or proteinase K Purification of parasporin-4 from inclusion bodies in E-coli by the treatment with pepsin Future Research References