Bacteriocins in Gram-positive bacteria have attracted much attention because many have a strong antimicrobial activity also against bacteria outside the genera of the producers. Lantibiotics and the pediocin-like bactericins have attracted most attention since they kill a broad spectrum of Gram-positive bacteria including important pathogens. But many other promising Gram-positive bacteriocins have been thoroughly characterized. Recent studies have shown that bacteriocins may playa role in the intestinal flora to protect us against the food-borne pathogens. Bacterial genome sequencing has demonstrated that there may be an arsenal of such compounds and we are only seeing the top of the iceberg. The present review gives a short outlook of the field of bacteriocins with focus on lactic acid bacteria and includes recent findings.
목차
Abstract Introduction Classification of Bacteriocins Class I : The Lantibiotics The Class II Bacteriocins Class IV : Circular Bacteriocins Target/Receptor of Class II One-peptide Bacteriocins Regulation of ClAss I and II Bacteriocin Production Perspectives Acknowledgments References
키워드
bacteriocinlactic acid bacteriaclassificationmodes of actiongene regulation
저자
Nes, Ingolf F. [ Laboratory for Microbial Gene Technology and Food Microbiology, Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Science ]
Yoon, Sung-Sik [ Department of Biological Resources and Technology, Yonsei University ]
Diep, Dzung B. [ Laboratory for Microbial Gene Technology and Food Microbiology, Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Science ]