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A Modified Process for Producing High Quantities of Bio-Germanium in Yeast and a Study of Its Oral Toxicity

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 16 Number 1 (2007.02)바로가기
  • 페이지
    pp.78-82
  • 저자
    Park, So-Young, Joo, Seong-Soo, Won, Tae-Joon, Chung, Jin-Woong, Lee, Sung-Hee, Oh, Sun-Woo, Lee, Do-Ik, Hwang, Kwang-Woo
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A79119

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원문정보

초록

영어
Since germanium has been shown to be beneficial for the treatment of diseases such as cancer and rheumatic arthritis, we developed an adapted process of bio-germanium preparation using inorganic germanium. In the present study we determined the optimal conditions for culturing yeast Saccharomyces cerevisiae (KCTC-1199), and the best concentrations of inorganic germanium for the adaptation process. The resulting method was successful at producing high quantities of germanium yeasts. The following are the culture conditions that obtained the highest level of productivity: an inorganic germanium concentration of 3,000-5,000 ppm, a pH of 6.5, a temperature of 35℃, and 20 hr of incubation time. In addition to this high-yield quantity study, we observed the acute oral toxicity of mice treated with Geranti Bio-Ge Yeast(R). We found no changes in body weight, or in the mortality between the control groups and the bio-germanium yeast group. There were also no digestive problems such as diarrhea that occurred in either group.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

Saccharomyces cerevisiae inorganic germanium adaptation process bio-germanium

저자

  • Park, So-Young [ Department of Cell and Molecular Biology, Feinberg School of Medicine and Institute of Neuroscience, Northwestern University ]
  • Joo, Seong-Soo [ Department of Immunology, College of Pharmacy, Chung Ang University ]
  • Won, Tae-Joon [ Department of Immunology, College of Pharmacy, Chung Ang University ]
  • Chung, Jin-Woong [ Korea Research Institute of Bioscience and Biotechnology ]
  • Lee, Sung-Hee [ GertantiPharm Ltd. ]
  • Oh, Sun-Woo [ GertantiPharm Ltd. ]
  • Lee, Do-Ik [ Department of Immunology, College of Pharmacy, Chung Ang University ]
  • Hwang, Kwang-Woo [ Department of Immunology, College of Pharmacy, Chung Ang University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 16 Number 1

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