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Assessment of the Potential Allergenicity of Genetically Modified Soybeans and Soy-based Products

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 바로가기
  • 통권
    Volume 15 Number 6 (2006.12)바로가기
  • 페이지
    pp.954-958
  • 저자
    Kim, Jae-Hwan, Lieu, Hae-Youn, Kim, Tae-Woon, Kim, Dae-Ok, Shon, Dong-Hwa, Ahn, Kang-Mo, Lee, Sang-Il, Kim, Hae-Yeong
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A79099

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원문정보

초록

영어
A comprehensive safety evaluation was conducted to assess the potential allergenicity of newly introduced proteins in genetically modified (GM) crops. We assessed the allergenicity of CP4 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) in GM soybeans. This assessment was performed by IgE immunoblotting with soy-allergic children's sera, amino acid sequence homology with known allergens, and the digestibility of CP4 EPSPS. No differences in IgE-antigen binding by immunoblotting were found between GM soy samples and the corresponding non-GM samples. Based on the comparison of EPSPS amino acid sequence homology with current allergen databases, no known allergen was found. In addition, CP4 EPSPS protein was rapidly digested by simulated gastric fluid (SGF). Taken together, these results indicate that GM soybeans have no allergenicity in children and are as safe as conventional soybeans.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

allergenicity 5-enolpyruvylshikimate-3-phosphate synthase GM soybeans immunoblotting; simulated gastric fluid

저자

  • Kim, Jae-Hwan [ Graduate School of Biotechnology and Institute of Life Sciences and Resources, Department of Food Science and Biotechnology, Kyung Hee University ]
  • Lieu, Hae-Youn [ Graduate School of Biotechnology and Institute of Life Sciences and Resources, Department of Food Science and Biotechnology, Kyung Hee University ]
  • Kim, Tae-Woon [ Graduate School of Biotechnology and Institute of Life Sciences and Resources, Department of Food Science and Biotechnology, Kyung Hee University ]
  • Kim, Dae-Ok [ Graduate School of Biotechnology and Institute of Life Sciences and Resources, Department of Food Science and Biotechnology, Kyung Hee University ]
  • Shon, Dong-Hwa [ Food Function Research Division, Korea Food Research Institute ]
  • Ahn, Kang-Mo [ Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine ]
  • Lee, Sang-Il [ Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine ]
  • Kim, Hae-Yeong [ Graduate School of Biotechnology and Institute of Life Sciences and Resources, Department of Food Science and Biotechnology, Kyung Hee University ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

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