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Isolation and Characterization of an Immunopotentiating Factor from Lactobacillus plantarum in Kimchi: Assessment of Immunostimulatory Activities

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 바로가기
  • 통권
    Volume 15 Number 6 (2006.12)바로가기
  • 페이지
    pp.877-883
  • 저자
    Lee, Jong-Hwa, Kweon, Dae-Hyuk, Lee, Seung-Cheol
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A79086

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원문정보

초록

영어
The immunostimulatory activities of Lactobacillus plantarum, the major microorganism in kimchi fermentations were investigated. Five strains of L. plantarum exhibited weak immunopotentiating activity, but L. plantarum PS-21 showed as strong a mitogenic activity as Bifidobacterium adolescentis M101-4, a known positive strain. It is of interest that, L. plantarum PS-21 stimulated proliferation of Peyer's patch cells, one of the most important tissues in the gut-associated lymphoreticular system. Cell' wall fractions from L. plantarum PS-21 also showed strong mitogenic activity compared with the soluble cytoplasmic fraction. A peptidoglycan fraction (PG) extracted from the cell wall of L. plantarum PS-21 was identified as an active mitogenic component when used in murine lymph node and spleen cell test systems. PG showed dose-dependent mitogenic activity and significantly enhanced antibody production in lymph node cells when studied in vitro. The lysosomal enzyme activity of murine peritoneal macrophages was increased when analyzed following injection of PG to the host animal. Furthermore, PG enhanced the production of cytokines such (TNF-a and IL-6) in the in vitro culture of RAW 264.7 macrophage cells.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

Lactobacillus plantarum peptidoglycan immunostimulating activities

저자

  • Lee, Jong-Hwa [ School of Bioresource Science, Andong National University ] Corresponding author
  • Kweon, Dae-Hyuk [ Department of Genetic Engineering, Sungkyunkwan University ]
  • Lee, Seung-Cheol [ Division of Food Science and Biotechnology, Kyungnam University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 15 Number 6

    피인용수 : 0(자료제공 : 네이버학술정보)

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