The goal of this study was to screen and characterize the physiological functions of Korean traditional wines (TW) and liquors (TL). Forty-two TW and TL were collected and evaluated for quality and cardiovascular activities. Ethanol content ranged from 9.0%~41%, and pH ranged from 3.0~7.8, and they also contained 0.01% to 0.67% of total acid. Samples contained a maximum of 2.0% of crude protein and 0.1%~14.0% of reducing sugar. Commercial CM-wine showed the highest antihypertensive angiotensin I-converting enzyme (ACE) inhibitory activity, 85.9%. The greatest fibrinolytic activity and platelet aggregation inhibitory activity were also found in commercial CM-wine (31.8U) and commercial SS2-wine (38.6 %), respectively. Commercial SHBI-liquor showed the highest HMG-CoA reductase inhibitory activity, 78%. The ACE inhibitor from commercial CM-wine was a peptide compound and also showed an antihypertensive effect in spontaneous hypertensive rats at a dosage of 1.5 mg/kg.
목차
Abstract Introduction Materials and Methods Results and Discussion Conclusion Acknowledgments References
키워드
cardiovascular activitiesangiotensin I-converting enzyme inhibitorKorean traditional wines and liquors
저자
Yu, Hyung-Eun [ Department of Life Science and Genetic Engineering, and Bio-medicinal Resources Research Center, Paichai University ]
Lee, Dae-Hyoung [ Department of Life Science and Genetic Engineering, and Bio-medicinal Resources Research Center, Paichai University ]
Lee, Ju-Hyun [ Department of Life Science and Genetic Engineering, and Bio-medicinal Resources Research Center, Paichai University ]
Choi, Sin-Yang [ Korea Food Research Institute ]
Lee, Jong-Soo [ Department of Life Science and Genetic Engineering, and Bio-medicinal Resources Research Center, Paichai University ]
Corresponding author