Earticle

초록

영어

Cellular components of Lactococcus lactis ssp. lactis (heat-killed whole cells, cytoplasm, and cell walls) were tested for their in vivo immunopotentiating activities. Peritoneal macrophages from mice injected intraperitoneally with cell-wall fractions exhibited significantly greater phagocytic activity than groups injected with whole cells or cytoplasm fraction. Cytotoxicity of natural-killer cells was highest in cytoplasm fractions. Production of cytokines (IFN-, IL-2, IL-6, and IL-12) in spleen cells was significantly higher when cellular components were injected intraperitoneally, and tended to be higher in whole-cell and cytoplasm groups than in cell-wall group. These results demonstrate lactic acid bacteria whole cells and their cytoplasm and cell-wall tractions have immunopotentiating activities.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

저자

• Kim, Ji-Yeon [ Department of Food Standard Evaluation, Korea Food & Drug Administration ]
• Lee, Seong-Kyu [ Department of Applied Biological Chemistry, The University of Tokyo ]
• Jeong, Do-Won [ School of Agricultural Biotechnology, and Center of Agricultural Biomaterials, Seoul National University ]
• Hachimura, Satoshi [ Department of Applied Biological Chemistry, The University of Tokyo ]
• Kaminogawa, Shuichi [ Department of Food Science and Technology, College of Bioresource Science, Nihon University ]
• Lee, Hyong-Joo [ School of Agricultural Biotechnology, and Center of Agricultural Biomaterials, Seoul National University ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664