A fraction (CMEx-AH-B) of water-soluble polysaccharides, showing selective antitumor activities, was isolated from the mycelia of solid cultured Agaricus blazei Murill by hot-water extraction, ethanol precipitation, and series of chromatography. Chemical characteristics of CMEx-AH-B, were as follows: carbohydrate content, 48%; monosaccharide composition, Man:Glu:Gal (2:93:5); molecular weight, 2x105; uronic acid content, 6.2%. Fundamental structure of CMEx-AH-B, was deduced as B-(1 → 6)-D-glucan with B-(1→ 3)-D-glucosidic side chains based on results of methylation and 13C NMR spectroscopic analyses.
목차
Abstract Introduction Materials and Methods Results and Discussion References
Chung, Ha-Yull [ Department of Food Science & Biotechnology, and Food & Biotechnology Research Center, Hankyong National University ]
Corresponding author
Cho, Young-Jun [ Department of Food Science & Biotechnology, and Food & Biotechnology Research Center, Hankyong National University ]
Kim, Tae-Wook [ Department of Food Science & Biotechnology, and Food & Biotechnology Research Center, Hankyong National University ]