Yook, Hong-Sun, Byun, Myung-Woo, Song, Hyun-Pa, Lee, Ju-Woon, Kim, Kwan-Soo, Kim, Kwang-Hoon, Lee, Ho-Joon, Kim, Dong-Ho
언어
영어(ENG)
URL
https://www.earticle.net/Article/A78705
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원문정보
초록
영어
The genotoxicological safety of fermented vegetables pasteurized by gamma irradiation was examined to consider the possibility of the application of irradiation for extending of fermented vegetables. A fermented vegetable was irradiated at 20 kGy to assure its toxicological safety even at a high dose of radiation. The Ames test with Salmonella typhimurium (TA98, TA100, TA1535, TA1537) and Escherchia coli (WP2), and the chromosomal aberration test in Chinese hamster lung (CHL) cells were performed. In vivo micronucleus test were conducted in mouse bone marrow cells. With or without metabolic activation, negative results were obtained in the Ames test and the chromosomal aberration test. In the micronucleus test, there was no enhancement in the formation of micronucleus, and there were no such significant differences between the irradiated and non-irradiated samples. The observed results indicated that, a level of 20 kGy of gamma irradiation on the fermented vegetable did not bring about any genotoxic effects under the described experimental conditions.
목차
Abstract Introduction Materials and Methods Results and Discussion Acknowledgments References
키워드
gamma irradiationKimchigenotoxicityAmes test
저자
Yook, Hong-Sun [ Department of Food and Nutrition, Chungnam National University ]
Byun, Myung-Woo [ Department of Radiation Food Science and Biotechnology, Korea Atomic Energy Research Institute ]
Song, Hyun-Pa [ Department of Radiation Food Science and Biotechnology, Korea Atomic Energy Research Institute ]
Lee, Ju-Woon [ Department of Radiation Food Science and Biotechnology, Korea Atomic Energy Research Institute ]
Kim, Kwan-Soo [ Greenpia Tech Co. ]
Kim, Kwang-Hoon [ Greenpia Tech Co. ]
Lee, Ho-Joon [ Korea Food Research Institute ]
Kim, Dong-Ho [ Department of Radiation Food Science and Biotechnology, Korea Atomic Energy Research Institute ]
Corresponding author