Lee, Jae-Seok, Kim, Hye-Yun, Park, Kap-Joo, Lee, Hyung-Hoan
언어
영어(ENG)
URL
https://www.earticle.net/Article/A78699
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원문정보
초록
영어
In this study, the ameliorating effect of soybean embryos on the impact of alcohol consumption was investigated on rat hepatocytes and in reducing total serum cholesterol levels and total serum lipid levels. Liver histology and two clinically important enzyme markers, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), of rats administered with both alcohol and soybean embryo were compared with a control group. The treatment regimen of soybean embryo significantly reduced the serum ALT and AST levels of the subjects, demonstrating the hepato-protective effects of soybean embryo. Electron microscopy indicated that the administration of soybean embryo preserved the important hepatocyte structures and prevented the presence of lipid droplets and secondary lysosomes. Furthermore, total cholesterol and total lipid levels were significantly reduced. These results indicate that treatment with soybean embryo can positively mediate the effects of alcohol on hepatocytes and general liver functions.
목차
Abstract Introduction Materials and Methods Results and Discussion Acknowledments References
키워드
soybean embryosoybeanrat hepatocytesalcohol
저자
Lee, Jae-Seok [ Department of Biological Sciences, Konkuk University ]
Kim, Hye-Yun [ Department of Biological Sciences, Konkuk University ]
Park, Kap-Joo [ Department of Biological Sciences, Konkuk University ]
Lee, Hyung-Hoan [ Department of Biological Sciences, Konkuk University ]
Corresponding author