In Young Bae, Yun Jeoung Chang, Hye Won Kim, Hyeon Gyu Lee
언어
영어(ENG)
URL
https://www.earticle.net/Article/A78606
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원문정보
초록
영어
Barley β-Glucan was subjected to chemical modification and the anticoagulant activity of the derivative was investigated. The barley β-Glucan was successfully sulfated, showing the degree of substitution calculated by elemental analysis of 0.40. In addition, the Fourier transform infrared (FT-IR) spectra of the derivative confirmed the sulfation, which generated two new absorption bands at 1,250/cm (S=O) and 810/cm (C-O-S) compared to the native. Specially, the anticoagulant activity of barley β-Glucan was created by sulfation, which increased in a concentration-dependent manner. This result demonstrated that the incorporation of sulfate groups into the β-Glucan structure added a blood clotting prevention effect.
목차
Abstract Introduction Materials and Methods Results and Discussion Acknowledgments References
키워드
barley B-glucansulfationanticoagulant activity
저자
In Young Bae [ Department of Food and Nutrition, Hanyang University ]
Yun Jeoung Chang [ Department of Food and Nutrition, Hanyang University ]
Hye Won Kim [ Department of Food and Nutrition, Hanyang University ]
Hyeon Gyu Lee [ Department of Food and Nutrition, Hanyang University ]
Corresponding author