Mi Soon Kim, Bin Kwon, Myeong Soo Park, Geun Eog Ji
언어
영어(ENG)
URL
https://www.earticle.net/Article/A78591
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Ginsenosides are responsible for the pharmacological and biological activities of ginseng. In this study, ginsenoside Rh1 and compound K were isolated and purified from fermented ginseng substrate and their anti-allergic effects were assessed in compound 48/80-induced anaphylactic shock model. The fermented ginseng substrate was extracted by methanol and ginsenoside Rh1 and compound K were efficiently purified by preparative high performance liquid chromatography (prep HPLC). Their quality and quantity were analyzed by liquid chromatography-mass spectrometer (LC-MS) and HPLC. Ginsenoside Rh1 showed better anti-allergic effects than compound K in compound 48/80-induced anaphylactic shock model. This study suggested that fermented ginseng extracts with enriched Rh1 may be utilized as a potential biomaterial of functional food for the alleviation of allergic symptoms.
목차
Abstract Introduction Materials and Methods Results and Discussion Acknowledgments References
키워드
anaphylactic shock modelcompound Kginsenoside Rhl
저자
Mi Soon Kim [ Department of Food and Nutrition, Research Institute of Human Ecology, Seoul National University ]
Bin Kwon [ Research Center, Bifido Inc ]
Myeong Soo Park [ Research Center, Bifido Inc, Department of Hoterl Culinary Art, Anyang Technical College ]
Geun Eog Ji [ Department of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Research Center, Bifido Inc., ]
Corresponding author