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Aqueous Extracts of Walnut (Juglans regia L.) and Nelumbo nucifera Seeds Reduce Plasma Corticosterone Levels, Gastric Lesions, and c-fos lmmunoreactivity in Chronic Restraint-stressed Mice

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 17 Number 4 (2008.08)바로가기
  • 페이지
    pp.713-717
  • 저자
    Dae Won Kim, In Koo Hwang, Ki-Yeon Yoo, Hua Li, Il-Jun Kang, Won-Kuk Moon, Moo-Ho Won, Seok Joong Kim, Daeseok Han, Dong-Woo Kim
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A78354

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원문정보

초록

영어
In the present study, chronic effects of the hot water extracts of walnut seed (Juglans regia L.) (WSE) and Nelumbo nucifera seed (NSE) were investigated in mice exposed to 2 hr of restraint stress each day for 4 weeks. Corticosterone levels in serum were significantly increased in the vehicle-treated stressed group (25㎍/dL) compared to that in the control group (13㎍/dL). This stress induced gastric redness and lesions. However, treatment with WSE and/or NSE significantly protected the stomach from this lesion by 50-60% compared to that in the vehicletreated group. In the amygdala, the administration of WSE and/or NSE also reduced the immediate early gene (c-fos) expression by 70-90% vs. the vehicle-treated group. These suggest that WSE and/or NSE may reduce the appearance of symptoms induced by stress and these materials are useful as anti-stress foods, as natural products tend to be relatively safe compared to chemical products.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

restraint stress corticosterone gastric lesion c-fos medial amygdale

저자

  • Dae Won Kim [ Central Research Center, Natural F&P Co., Ltd ]
  • In Koo Hwang [ Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University ]
  • Ki-Yeon Yoo [ Department of Anatomy and Neurobiology, College of Medicine, Hallym University ]
  • Hua Li [ Department of Anatomy and Neurobiology, College of Medicine, Hallym University ]
  • Il-Jun Kang [ Department of Food Science and Nutrition, Division of Life Science, Hallym University ]
  • Won-Kuk Moon [ Central Research Center, Natural F&P Co., Ltd ]
  • Moo-Ho Won [ Department of Anatomy and Neurobiology, College of Medicine, Hallym University ]
  • Seok Joong Kim [ Department of Food and Nutrition, Dongduk Women's University ]
  • Daeseok Han [ Food Processing and Post-harvest Technology Division, Korea food Research Institute ]
  • Dong-Woo Kim [ Central Research Center, Natural F&P Co., Ltd ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 17 Number 4

    피인용수 : 0(자료제공 : 네이버학술정보)

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