현재 위치
Home
[원보]
인공심장판막치환환자의 응급센터 내원시 warfarin에 의한 합병증에 관한 연구
Analysis of Warfarin-induced Complications in Patients with Mechanical Heart Valve Replacement in Emergency Center
-
- 발행기관
- 한국임상약학회 바로가기
-
- 간행물
- 한국임상약학회지 KCI 등재 바로가기
-
- 통권
- 제17권 제2호 (2007.12)바로가기
-
- 페이지
- pp.70-75
-
- 저자
-
- 언어
- 한국어(KOR)
-
- URL
- https://www.earticle.net/Article/A63345
※ 기관로그인 시 무료 이용이 가능합니다.
4,000원
원문정보
초록
- 영어
- Purpose: This study was to evaluate the factors on bleeding complications and thromboembolism in patients on warfarin with mechanical heart valves visiting emergency center. Methods: Among 560 patients who were operated at Y Cardiovascular Hospital between November 2001 and October 2006, we reviewed the records of 83 patients who had mechanical heart valve and visited emergency center. Results: There were 6 major thromboembolic events, 18 major bleeding events and 25 minor bleeding events from 83 patients who visited emergency center. The mean international normalized ratio (INR) was 4.30±13.29 in patients visiting emergency center, 6.07±3.86 in patients with major bleeding, and 5.89±2.80 in patients with minor bleeding complication. There was statistically significant difference in INR between bleeding complication groups and no bleeding groups (p = 0.001 in patients with major bleeding, p<0.0001 in patients with minor bleeding). However, there was no difference in time in therapeutic range (TTR) when the therapeutic target range of INR was 1.8~3.0 (p = 0.730). With risk analysis, serum albumin level was significantly low and weekly warfarin dose was significantly high in patients with bleeding complication (p≤0.05). Conclusions: There were differences in the values of INR, albumin and weekly warfarin dose among major bleeding, minor bleeding and no complication groups even though TTR was not significantly different among the groups. To reduce anticoagulation related complications, close monitoring and systemic anticoagulation education should be offered by experienced and knowledgeable pharmacists.
목차
ABSTRACT
연구방법
연구대상
자료수집 내용
분석내용
통계방법
연구결과
고찰
결론
참고문헌
키워드
Warfarin mechanical heart value bleeding thranboembolism저자
간행물 정보
발행기관
-
- 발행기관명
- 한국임상약학회 [Korean College of Clinical Pharmacy]
- 설립연도
- 1
- 분야
- 의약학>약학
- 소개
- 합리적 약물치료(rational pharmacotherapy)의 보장 및 증진을 궁극목적으로 하며 이를 달성하기 위해 임상약학의 발전과 회원 상호간의 친목을 도모한다.
간행물
-
- 간행물명
- 한국임상약학회지 [Korean Journal of Clinical Pharmacy]
- 간기
- 계간
- pISSN
- 1226-6051
- 수록기간
- 1991~2026
- 등재여부
- KCI 등재
- 십진분류
- KDC 518 DDC 615
이 권호 내 다른 논문 / 한국임상약학회지 제17권 제2호
피인용수 : 0건 (자료제공 : 네이버학술정보)
함께 이용한 논문 이 논문을 다운로드한 분들이 이용한 다른 논문입니다.
출처 : 네이버학술정보
0개의 논문이 장바구니에 담겼습니다.