Objectives: This study aimed to synthesize evidence on the clinical and economic outcomes of designated ward pharmacist services in South Korea, assess the certainty of available evidence, and identify current research gaps and methodological limitations to inform directions for future research. Methods: A systematic search of five electronic databases identified 22 eligible studies published between January 2010 and February 2026, comprising 12 comparative studies and 10 cross-sectional analyses. Evidence certainty was assessed using the GRADE methodology. Results: Designated pharmacist interventions demonstrated positive clinical trends, including reductions in inappropriate prescribing, decreased 30-day readmission rates, and improved pain management. Physician acceptance rates for these interventions ranged from 78.7 to 98.5%, with significant increases observed in most comparative studies. However, lower acceptance rates were reported in specific patient populations (54.4-68.5%), such as those with renal impairment or hematologic conditions, suggesting that patient characteristics may influence acceptance. Regarding healthcare provider perception, clinician awareness and satisfaction regarding ward pharmacist services were high, ranging from 89.9 to 91.3% and 70.0 to 79.7%, respectively. Despite reported cost-reduction trends across nine studies, inconsistent methods and omitted labor costs limited definitive conclusions. Conclusion: Designated ward pharmacists have potential to act as vital cognitive assets in enhancing medication safety and economic benefits. Nevertheless, GRADE evidence certainty remains low to very low, constrained by non-randomized single-center designs. Standardized, prospective research is warranted to support expanded implementation.
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ABSTRACT 연구방법 자료원 및 검색 전략 연구대상 선정기준 자료 추출 질평가 근거 수준 평가 연구결과 문헌 선정 결과 포함 연구의 기본 특성 전담약사의 중재 활동 현황 전담약사 중재 평가 변수 전담약사 중재가 임상 결과에 미치는 효과 전담약사 활동 및 운영 현황 질 평가 결과 및 방법론적 한계 고찰 주요 결과 요약 결과 해석 및 선행연구 비교 GRADE 적용에 따른 근거 수준 평가 연구의 강점과 한계 후속 연구 및 연구자에 대한 제언 결론 감사의 말씀 이해 상충 References