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Session 4: Bio Science for Co-Prosperity

Exploring Potential of Antarctic Moss : Unveiling Its Scientific and Biotechnological Applications

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  • 발행기관
    선문효정학술연구회 바로가기
  • 간행물
    선문효정학술연구회 학술대회 프로시딩 바로가기
  • 통권
    Proceedings of THE 5th INTERNATIONAL CONFERENCE OF HYOJEONG ACADEMY (2025.02)바로가기
  • 페이지
    pp.107-112
  • 저자
    Hirotake Yamaguchi, Ryoichi Yamada, Kristina Lama, Tae-Jin Oh
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A489352

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원문정보

초록

영어
Antarctic mosses represent an untapped treasure trove of bioactive compounds with potential applications in a variety of fields. The aim of this study was to evaluate the bioactivity of extracts from Antarctic mosses using a combination of metabolomic and in silico analyses to identify active compounds. In the first bioactivity assay, significant antioxidant and enzyme inhibitory activities were observed in selected moss extracts. The extract that exhibited the highest biological activity was subjected to comprehensive metabolomic profiling using LC-MS/MS to identify the major secondary metabolites. Molecular docking studies were performed on these metabolites to predict their binding affinities and interactions with target proteins to elucidate potential mechanisms underlying the observed biological activities. These findings suggest that Antarctic mosses contain unique metabolites with promising biological activities and provide insight into adaptive mechanisms in extreme environments. This study highlights the potential pharmaceutical and biotechnological applications of compounds derived from the moss and paves the way for further in vitro and in vivo investigations to validate their efficacy.

목차

Abstract
1. Introduction
2. Materials and Methods
2.1. Sample Collection and Extraction
2.2. Metabolite Profiling
2.3. In silico Pharmacological Analysis
3. Results
3.1. In vitro results
3.2. LC-MS/MS Profiling of Methanol Extract from Warnstorfia fontinaliopsis
3.3. Molecular docking with lipase
3.4. Computational pharmacokinetics analysis
4. Discussion
5. Conclusions
References

키워드

Antarctic moss Metabolomics profiling molecular docking.

저자

  • Hirotake Yamaguchi [ Department of Life Science and Biochemical Engineering, Sun Moon University, Asan 31460, Korea ]
  • Ryoichi Yamada [ Department of Life Science and Biochemical Engineering, Sun Moon University, Asan 31460, Korea ]
  • Kristina Lama [ Department of Life Science and Biochemical Engineering, Sun Moon University, Asan 31460, Korea ]
  • Tae-Jin Oh [ Department of Life Science and Biochemical Engineering, Sun Moon University, Asan 31460, Korea ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    선문효정학술연구회 [Sun Moon Hyojeong Academy Society]
  • 설립연도
    2023
  • 분야
    복합학>학제간연구
  • 소개
    Journal of Hyojeong Academia aims to serve as a global platform where researchers and scholars of various disciplines can contribute ideas for our sustainable global community of Co‐existence, Co‐prosperity, and Co‐righteousness. The journal is a multidisciplinary, open‐access, internationally peer‐reviewed academic journal, and it invites all areas of research conducted in the spirit of post materialism including studies centering on God, studies unifying religions and sciences, and studies on all aspects of Co‐existence, Co‐prosperity, and Co‐righteousness.

간행물

  • 간행물명
    선문효정학술연구회 학술대회 프로시딩
  • 간기
    반년간
  • 수록기간
    2023~2026
  • 십진분류
    KDC 238 DDC 289

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