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Regional Disparities in COVID-19 Burden, and Association between Severe SARS-CoV-2 Infection Outcomes and Metabolic Disorders : Ecological Study of the Pre-Omicron Era of the Pandemic

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  • 발행기관
    선문효정학술연구회 바로가기
  • 간행물
    선문효정학술연구회 학술대회 프로시딩 바로가기
  • 통권
    Proceedings of THE 2nd INTERNATIONAL CONFERENCE OF HYOJEONG ACADEMY 2023 (2023.08)바로가기
  • 페이지
    pp.81-84
  • 저자
    Nlandu Roger NGATU, Christian Wansu MAPONG, Alpha Ngansaki KINGO
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A489222

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초록

영어
Evidence from epidemiologic studies indicate that metabolic disorders such as obesity and diabetes are high-risk factors for severe COVID-19 and related mortality. Over 30% of people with COVID-19 who require hospitalization suffer from diabetes. This study explored the association between severe COVID-19 outcomes and metabolic disorders, at regional level, across countries of the Organization for Economic Cooperation and Development (OECD). We conducted an ecological study using COVID-19 data of high- and middle-income countries belonging to OECD (N=38), with an estimated total population of 1.4 billion, divided into 3 regions: region 1: Europe& Middle-east; region 2: the Americas (north, central & south America); region 3: East-Asia & Pacific region. The main outcome variables were: (1) COVID-19 case fatality rate (COVID-19 CFR) and (2) the disability-adjusted life years (COVID-19 DALYs). The country-level COVID-19 CFR were calculated using freely available cumulative COVID-19 cases and deaths statistics; similarly, data on overweight & obese population rate, diabetes prevalence and regional COVID-19 DALYs were obtained from both OECD and WHO databases. Overall cumulative deaths were 65,000 per million; regional COVID-19 CFR was highest in the Americas, 2.4(2.6) %. Highest DALYs were found in East-Asia & Pacific region, 22 (0.0) years. Pearson correlation analysis showed that diabetes prevalence was correlated with both COVID-19 DALYs (OR=0.52; p=0.009), and COVID-19 CFR (OR=0.58; p=0.000). The logistic regression analysis showed that diabetes prevalence was strongly associated with COVID-19 CFR (OR=2.65 (1.8); 95%CI: 1.71–9.97; p=0.038) and COVID- 19 DALYS (OR=1.39 (0.3); 95%CI: 1.66-2.02; p=0.046). Findings from this study confirm that diabetes is as a major predictor of severe COVID-19 outcomes in OECD countries at regional level.

목차

Abstract
1. Introduction
2. Materials and Methods
2.1. Study design and population
2.2. Main outcome variables and definitions
2.3. Ethical consideration and data analysis
3. Results
3.1. Regional Demographic, Health and COVID-19-related Indicators in the pre-Omicron phase of the pandemic
3.2. Relationship between Metabolic Disorders (overweight/obesity, diabetes) and COVID-2019 burden-associated healthindicators (CFR, DALYs) in the pre-Omicron Phase of the Pandemic
4. Discussion
References

키워드

COVID-19 Case fatality rate Diabetes Disability adjusted life years Metabolic disorder.

저자

  • Nlandu Roger NGATU [ Department of Public Health, Kagawa University Faculty of Medicine, Kagawa 761-793, Japan/ Congo-Japan Communicable and Noncommunicable Diseases Research Group, Kongo central, Democratic Republic of the Congo (DRC) ] Corresponding Author
  • Christian Wansu MAPONG [ Congo-Japan Communicable and Noncommunicable Diseases Research Group, Kongo central, Democratic Republic of the Congo (DRC)/ Division of Health Sciences, Institute Superior Technique SongHwa (ISTS), Kinshasa, DRC ]
  • Alpha Ngansaki KINGO [ Congo-Japan Communicable and Noncommunicable Diseases Research Group, Kongo central, Democratic Republic of the Congo (DRC) ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    선문효정학술연구회 [Sun Moon Hyojeong Academy Society]
  • 설립연도
    2023
  • 분야
    복합학>학제간연구
  • 소개
    Journal of Hyojeong Academia aims to serve as a global platform where researchers and scholars of various disciplines can contribute ideas for our sustainable global community of Co‐existence, Co‐prosperity, and Co‐righteousness. The journal is a multidisciplinary, open‐access, internationally peer‐reviewed academic journal, and it invites all areas of research conducted in the spirit of post materialism including studies centering on God, studies unifying religions and sciences, and studies on all aspects of Co‐existence, Co‐prosperity, and Co‐righteousness.

간행물

  • 간행물명
    선문효정학술연구회 학술대회 프로시딩
  • 간기
    반년간
  • 수록기간
    2023~2026
  • 십진분류
    KDC 238 DDC 289

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