Maximal oxygen uptake (VO2max) represents a fundamental index of aerobic fitness and integrative cardiopulmonary performance. Although whole-body composition—particularly skeletal muscle mass and adiposity—is known to influence VO2max, the relative contributions of peripheral muscle mechanical properties and local muscle morphology remain incompletely understood. In particular, the extent to which neuromuscular contractile characteristics assessed by tensiomyography (TMG) provide additional explanatory value beyond conventional body composition variables has not been fully clarified. Thus, this study aimed to identify decisive peripheral determinants of VO2max by examining the combined contributions of skeletal muscle mass (SMM), fat mass, TMG-derived contractile indices, and ultrasound-based muscle thickness. Thirty-three healthy adults participated in this cross-sectional study. Whole-body composition variables were assessed using standardized procedures. Contractile properties of the vastus lateralis were evaluated using TMG, with maximal radial displacement (Dm) and relaxation time (Tr) analyzed as indices of neuromuscular mechanical function. Ultrasound imaging was used to quantify vastus lateralis muscle thickness as a structural marker of peripheral muscle morphology. VO2max was determined using graded exercise testing under standardized laboratory conditions. Pearson correlation analysis and multiple linear regression were performed to identify independent predictors of VO2max. It demonstrated significant negative associations with fat mass and leg skinfold thickness and positive associations with RDm and femur length (p < 0.05). In multiple regression analysis, fat mass and TMG-derived relaxation time (Tr) emerged as significant independent negative predictors of VO2max (p < 0.05), indicating that increased adiposity and slower neuromuscular relaxation characteristics were associated with reduced aerobic capacity. SMM showed a positive contribution at a trend level but did not remain an independent predictor after adjustment. In contrast, vastus lateralis muscle thickness was not independently associated with VO2max after accounting for whole-body composition and neuromuscular mechanical variables. As a conclusion, these findings suggest that whole-body adiposity and peripheral neuromuscular mechanical properties represent key determinants of VO2max, whereas local muscle thickness alone provides limited independent explanatory value.
저자
Woo-Young Kim [ Department of Physical Education, Graduate School of Hanseo University/Research Institute of Sports and Industry Science, Hanseo University, Seosan, Korea ]
Jung-Soo Park [ Department of Physical Education, Graduate School of Hanseo University, Seosan, Korea ]
Yong-Seok Jee [ Department of Physical Education, Graduate School of Hanseo University/Research Institute of Sports and Industry Science, Hanseo University, Seosan, Korea ]
Corresponding Author