Earticle

초록

영어

Cancer statics in Korea has been the highest causes of death with steadily increasing. In annual rate of change, the most prevalent cancer was prostate cancer in male. Incidence rates of prostate cancer have been rising in South Korea, with change in intake of high fat western diet, reproductive patterns, lack of physical activity, obesity, and rising stress level the main contributory. Therefore to find obesity as risk factors on prostate cancer,assess to abdominal visceral fat. The study was case – control study and approved by the Institutional Review Board of the National Cancer Center(NCC2014-0124). The patient groups were set as newly diagnosed cancer patients(prostate cancer who visited at the Korean National Cancer Center hospital from August 1st, 2014 to January 6st, 2015. Undiagnosed cancer person as control group, who visited Korean National Cancer Center hospital for the health examination service by national health insurance from September 1st, 2009 to September 30th, 2014. The prostate cancer patients were 52 male aged ranges from 51 to82 years with a mean age of 66.1 ± 7.1 years old and that of the control participants were 50 male aged ranges from 59 to 75 years with a mean age of 64 years old. All cancer patients were only for a newly diagnosed cancer without any related to cancer treatment as take any chemotherapy, radiation therapy and surgery before the start of the study. The study on prostate cancer was conducted on a 3.0 Tesla Achieva and Achieva TX MR system(Philips Medical Systems, Best, The Netherlands). Measuring abdominal fat was used to approximate a level at the umbilicus or the fourth lumbar vertebra, which is a valid virtually all the information on abdominal fat in human. All patient’s profile information(height, weight, tumor size, lymph node, estrogen, and progesterone receptor) obtained from institutional electronic medical record(EMR). There were no significant associations between personality factors while risk of breast cancer was a positive first degree of family history with moderate and moderate inverse association with education level. Effect of physical activity was show stronger inversely association in hormone positive groups. Prostate cancer patients had a higher intake pork meat(p = 0.01 for pork belly) and lower intake fruits. Compared with controls, cases had a higher abdominal fat ratio, animal lipid lipid(p = 0.07 adjusted for total calories), and lower intake of dietary fiber(p = 0.02 adjusted for total calories). There were no correlation between total calories intake and all of anthropometric measurements(waist circumference, BMI, abdominal fat ratio). Abdominal total fat was highest positive correlation with all of anthropometric measurements p < 0.001), exclude abdominal fat ratio(r = 0.43). There were no association between BMI or waist circumference and PSA or Gleason pathological score, but abdominal fat was association with prostate cancer Gleason score(β = 0.5, p = 0.001). In conclusion, this study shows that abdominal fat ratio is useful as an indicator of risk factor on breast and prostate cancer as well malignancy

목차

Abstract
Ⅰ. Introdution
Ⅱ. Materials and Methods
2.1. Study design and Subjects
2.2. Participants information
2.3. Abdominal fat ratio
2.4. Analysis
III. Results
3.1. Comparison of characteristic and distribution in case control study
3.2. Association with predict clinical stage in prostate cancer patients
IV. Discussions
References

키워드

저자

• 김명성 [ Myeong-Seong Kim | 국립암센터 방사선과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한디지털의료영상학회논문지 [Korean Journal of Digital Imaging in Medicine]

• 간기

  연3회

• pISSN

  1976-7641

• 수록기간

  1995~2026

• 십진분류

  KDC 510 DDC 610