Effects of Collagen and Keratin Peptide Treatments on the Thickness and Cuticle Morphology of Bleach-Damaged Hair under Thermal and Non-Thermal Conditions
We investigated the restorative effects of collagen peptide (CP) and keratin peptide (KP) treatments on hair fibers damaged through repeated 6% H₂O₂ bleaching. To evaluate the independent and combined influences of protein type and thermal activation, we designed a factorial experiment (CP × KP × heat) and analyzed hair thickness and cuticle morphology using a linear mixed-effects model (LMM) with tress-level random effects. We also performed multiplicity-adjusted comparisons and reported standardized effect sizes to ensure statistical robustness. We found that heat activation significantly enhanced the efficacy of both CP and KP, with the combined c4k1 condition yielding the greatest improvements in fiber diameter and cuticle surface integrity. SEM imaging confirmed reductions in cuticle lifting, fragmentation, and surface irregularities, especially under thermal activation. We demonstrate that protein synergy and heat activation are key determinants in restoring chemically damaged hair, providing scientific evidence for the development of advanced functional hair-care treatments.
목차
Abstract 1. Introduction 2. Materials 2.2 Methods 3. Results 3.1 Changes in Hair Thickness by Concentration of Collagen and Keratin Peptide Treatments 3.2 Changes in Cuticle Surface Morphology After Collagen and Keratin Peptide Treatments 4. Conclusion Reference