Activities of daily living (ADL) and instrumental ADL (IADL), main indica-tors of functional independence in older adults, are closely associated with depression and social networks and represent a critical determi-nant of well-being. Despite the growing body of research, both original and review articles to date have been limited in their ability to provide a comprehensive and coherent explanation of the interrelationships among these three domains, largely due to methodological constraints. Accordingly, this study systematically reviewed a wide range of publi-cations addressing functional ability, depression, and social networks in older adults, with the aim of providing evidence-based insights to in-form strategies for maintaining well-being and preparing for functional decline in aging populations. The synthesized findings indicate that de-clines in functional ability, as reflected by impairments in IADL/ADL, are associated with reduced instrumental ADL, increased depressive symp-toms, and decreased social participation, collectively contributing to a self-reinforcing cycle of functional and psychological deterioration. No-tably, this review demonstrates that while functional disability increases the risk of depression, robust social networks serve as protective fac-tors that mitigate both functional and psychological decline.
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Abstract INTRODUCTION MATERIALS AND METHODS Study design Study selection and data extraction Inclusion and exclusion criteria Quality assessment of included studies Research analysis and presentation method RESULTS Results of quality assessment of included studies Interrelationship between functional ability and depression in older adults Interrelationship between functional ability and social networks in older adults Interrelationship between depression and social networks in older adults DISCUSSION CONFLICT OF INTEREST ACKNOWLEDGMENTS REFERENCES