Earticle

초록

영어

Sarcopenia is a progressive and generalized skeletal muscle disorder characterized by the accelerated loss of muscle mass and function. It is associated with increased morbidity and mortality, particularly in older adults. According to the World Health Organization (WHO), the global population aged 60 years and older has doubled since 1980 and is projected to reach 2 billion by 2050, with more than 400 million individuals aged 80 years or older. As aging progresses, older adults experience a decline in mTORC1 (mammalian target of rapamycin complex 1) signaling activity, which plays a crucial role in protein synthesis and muscle maintenance. This leads to reduced anabolic response and impaired muscle protein synthesis. Therefore, adequate intake of essential amino acids, particularly those containing leucine, is important for preventing and managing sarcopenia in the elderly. Livact®, a branched-chain amino acid (BCAA) formulation containing leucine, isoleucine, and valine, has gained attention as a potential therapeutic option for sarcopenia. Studies suggest that combining Livact® supplementation with resistance exercise can significantly improve physical function, increase muscle mass, and enhance muscle strength in older adults. This evidence supports the clinical utility of BCAA supplementation, particularly Livact®, in the management of sarcopenia among the elderly population.

목차

Abstract
서론
본론
1. LivactⓇ의 성분
2. BCAA(branched-chain amino acids)
결론
참고문헌

키워드

저자

• Jae Wang Choi [ 최재왕 | Yonsei Leaders Neurosurgery Clinic, 181, Hoeryong-ro, Uijeongbu-si, Gyeonggi-do, Republic of Korea ]
• Jung Eun Kim [ 김정은 | Department of Anesthesiology and Pain Medicine, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Pain Bulletin

• 간기

  반년간

• pISSN

  2951-3782

• 수록기간

  2022~2025

• 십진분류

  KDC 514 DDC 617