Earticle

초록

영어

Background: Accurate quantification of surface dose is critical in radiation therapy, particularly for patients with breast cancer, for whom the risk of cutaneous toxicity is substantial. In this study, we evaluated the clinical feasibility of a novel flexible radiochromic film specifically designed to improve adhesion and usability on curved anatomic surfaces. Materials and Methods: The study prospectively enrolled 20 patients with breast cancer undergoing volumetric modulated arc therapy. Surface dose was measured using flexible radiochromic film placed near the surgical scar and close to the isocenter. Calibration curves were established using a 6 MV photon beam with flattening filter free and without, and the film response was analyzed in both transmission and reflection scanning modes. The measured surface doses were then compared with those calculated by the treatment planning system (TPS). Results and Discussion: The flexible radiochromic film demonstrated excellent sensitivity in the 1.5–2.5 Gy dose range, with superior performance observed in the transmission scanning mode. The film adhered securely to skin without requiring additional fixation and was removed without causing discomfort to the patient. Notably, substantial discrepancies were found between the measured and TPS-calculated surface doses, underscoring the limitations of a TPS in accurately modeling skin dose. Conclusion: Flexible radiochromic film demonstrated dosimetric performance similar to that of conventional films while offering enhanced flexibility and ease of clinical use. Given the significant uncertainty in TPS-based surface-dose estimation, the film provides accurate and practical in vivo surface-dose assessment in breast cancer radiotherapy.

목차

ABSTRACT
Introduction
Materials and Methods
1. Patient Selection
2. Film Processing (Calibration, Scanning, and Analysis)
3. Measuring In Vivo Surface Dose
4. Comparing Film Results with TPS Estimates
5. Statistical Analysis
Results and Discussion
Conclusion
Article Information
References

키워드

저자

• Jin Jegal [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea ]
• Jin Dong Cho [ Department of Radiation Oncology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea ]
• Jung-In Kim [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea ]
• Chang Heon Choi [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea ]
• Bum-Sup Jang [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea ]
• Jin Ho Kim [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea ]
• Kyung Hwan Shin [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Republic of Korea ]
• So-Yeon Park [ Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea; Department of Radiation Oncology, Veterans Health Service Medical Center, Seoul, Republic of Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629