Earticle

초록

영어

This study investigated the effects of 4-week and 8-week moderate-in-tensity aerobic exercise on body composition and markers of inflamma-tion and oxidative stress in middle-aged obese Hispanic females, with a particular focus on assessing these changes independently of fat mass reduction. A total of 35 participants were randomly assigned to either an exercise group or a control group for an eight-week intervention. The exercise group performed treadmill-based aerobic training at 55% of maximal oxygen consumption, with a fixed workload adjusted for body mass and a progression from three to four weekly sessions. Body composition was assessed using dual-energy x-ray absorptiometry, and blood samples were collected at baseline, 4 weeks, and 8 weeks to analyze tumor necrosis factor-alpha (TNF-α), C-reactive protein, adi-ponectin, total antioxidant status (TAS), and 8-hydroxydeoxyguanosine (8-OHdG). After 8 weeks, the exercise group showed significant reduc-tions in body fat percentage, TNF-α, and 8-OHdG, alongside an increase in TAS. Notably, by week 4, significant decreases in TNF-α and increases in TAS were observed despite no measurable changes in body weight or fat mass, indicating an early anti-inflammatory and antioxidative re-sponse to exercise independent of adiposity reduction. The findings at 4 weeks suggest that moderate aerobic exercise can independently re-duce inflammation and oxidative stress, even before measurable fat loss occurs. These improvements were further enhanced by fat loss af-ter 8 weeks, indicating that moderate aerobic exercise may reduce the risk of obesity-related disorders in middle-aged obese females, both through direct anti-inflammatory effects and by promoting fat loss.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Study participants
Experimental design
Measurements
Exercise intervention
Data analysis
RESULTS
Physical characteristics
Markers of inflammation and oxidative stress
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES

키워드

저자

• Kyung-Shin Park [ Department of Health Sciences, College of Nursing and Health Sciences, Texas A&M International University, Laredo, TX, USA ] Corresponding Author
• Paola Canales Gonzalez [ Department of Health Sciences, College of Nursing and Health Sciences, Texas A&M International University, Laredo, TX, USA ]
• Miguel Nieto [ Department of Health Sciences, College of Nursing and Health Sciences, Texas A&M International University, Laredo, TX, USA ]
• Brett S. Nickerson [ School of Health and Rehabilitation Sciences, Ohio State University, Columbus, OH, USA ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613