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Bioactive and Functional Activities of Mycelial Extracts of Gloeostereum incarnatum

첫 페이지 보기
  • 발행기관
    한국버섯학회 바로가기
  • 간행물
    버섯 바로가기
  • 통권
    제29권 2호 통권 51호 (2025.10)바로가기
  • 페이지
    pp.80-80
  • 저자
    Ji Min Woo, Yeon Jun Jeong, Kyoung Tae Lee, Aehyeon Nam, Jin Boo Jeong, Youngki Park
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A475299

원문정보

초록

영어
This study systematically evaluated the anti-inflammatory and whitening activities of Gloeostereum incarnatum, along with metabolite profile changes according to cultivation substrate composition. Crude extract (CE) and solvent-partitioned fractions (HEF, DCMF, EAF) were tested for nitric oxide (NO) inhibition in LPS-stimulated RAW264.7 macrophages, melanin synthesis suppression in α -MSH-induced B16F10 melanoma cells, and cytotoxicity in HCT116 colon cancer cells. Furthermore, primordia grown on various sawdust media supplemented with agricultural by products were analyzed by HPLC to compare metabolite patterns. The DCMF and EAF fractions significantly inhibited NO and melanin production in a concentration dependent manner, without detectable cytotoxic effects at 50 μg/mL. HPLC chromatograms revealed distinct peak profiles depending on substrate composition, with rice bran containing media showing intensified peaks presumed to represent active compounds. These findings indicate that the DCMF and EAF fractions of G. incarnatum hold strong potential as natural agents for inflammation control and skin-whitening, and highlight the importance of substrate formulation in optimizing bioactive metabolite yield.

키워드

Gloeostereum incarnatum Anti-inflammatory activity Whitening effect Solvent fraction Substrate composition

저자

  • Ji Min Woo [ Forest Microbiology and Application Division, Department of Forest Bio-resources, National Institute of Forest Science, Suwon, 16631, Korea ]
  • Yeon Jun Jeong [ Forest Microbiology and Application Division, Department of Forest Bio-resources, National Institute of Forest Science, Suwon, 16631, Korea ]
  • Kyoung Tae Lee [ Forest Microbiology and Application Division, Department of Forest Bio-resources, National Institute of Forest Science, Suwon, 16631, Korea ]
  • Aehyeon Nam [ Forest Microbiology and Application Division, Department of Forest Bio-resources, National Institute of Forest Science, Suwon, 16631, Korea ]
  • Jin Boo Jeong [ Department of Forest Science, Gyeongkuk National University, Andong, Gyeongsangbuk 36729, Republic of Korea ]
  • Youngki Park [ Forest Microbiology and Application Division, Department of Forest Bio-resources, National Institute of Forest Science, Suwon, 16631, Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국버섯학회 [The Korean Society of Mushroom Science]
  • 설립연도
    1997
  • 분야
    농수해양>농학
  • 소개
    우리나라의 버섯 연구와 관련 산업의 발전에 기여하고 버섯관련 연구자와 관련산업 종사자간의 학술정보 등의 교류를 목적으로 한다.

간행물

  • 간행물명
    버섯 [Mushroom]
  • 간기
    반년간
  • 수록기간
    1997~2025
  • 십진분류
    KDC 525 DDC 635

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