So-Young Lee, In-Woo Kim, Heui-Sam Lee, Joon-Ha Lee, You-Young Jo
언어
한국어(KOR)
URL
https://www.earticle.net/Article/A474221
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영어
Purpose: Edible insects are increasingly recognized as sustainable resources with potential health benefits. In this study, we analyzed the antioxidant and anti-inflammatory effects of Tenebrio molitor larval oil (TMO) for resource-circulating economic practice and the development of the sustainable edible insect industry based on the value of upcycling. Methods: TMO was extrcted by direct compression, and its antioxidant activity (DPPH radial sacvenging activity and ABTS radial sacvenging activity) and anti- inflammatory activity (NO, TNF-α, IL-1β, and IL-6 production) were evaluated. Results: We observed that both the antioxidant and anti-inflammatory activities of TMO increased in a concentration-dependent manner. Specifically, antioxidant activity rose with increasing concentrations, while production of inflammatiry mediators (NO, TNF-α, IL-1β, and IL-6) was inhibied in the same pattern. The most effect was observed at the highest concentration (75 μL/mL). Conclusion: These findings suggest that the concentration of TMO is crucial for optimizing its anti-inflammatory and antioxidant effects. Future studies, including animal experiments and clinical trials, are needed to confirm its safety and effectiveness. With such validation TMO may have broad potential for application as a health-functional food, a pharmaceutical auxiliary material, and an active ingredient in anti-inflammatory cosmetics.
한국어
목적: 본 연구에서는 식용곤충 오일을 업사이클링의 가치에 기반을 두고 자원 순환 경제 실천과 지속가능한 식용곤충 산업의 발전 을 위해 갈색거저리 유충 오일의 항산화 및 항염증의 생리활성 물질을 분석하였다. 방법: 직접 압착 추출한 갈색거저리 유충 오일의 항산화 활성(DPPH radical activitiy과 ABTS radical activitiy) 및 항염증 활성(NO, TNF-α, IL-1β 및 IL-6)을 측정하였다. 결과: 직 접 압착하여 추출한 갈색거저리 유충 오일의 항산화 활성(DPPH radical activitiy과 ABTS radical activitiy)은 농도가 증가할수록 항 산화 활성이 높았으며, 항염증 활성(NO, TNF-α, IL1β 및 IL-6)도 농도 의존적으로 억제되었다. 결론: 갈색거저리 유충 오일은 농 도의존적으로 항산화 활성을 증가시키고, 염증성 사이토카인(TNF-α, IL-6 및 IL-1β)의 생성을 억제하는 효과를 확인하였으며, 75 μL/mL의 가장 높은 농도에서 두드러진 효과가 나타났다. 이는 곤충 오일의 농도 조절이 항염 및 항산화 효능의 최적화에 중요 한 역할을 한다는 점을 예측할 수 있다. 향후 동물모델 및 임상 연구를 통해 안전성 및 유효성을 검증함으로써 건강기능식품, 의약 품 보조 소재, 항염 코스메디컬 등 다양한 산업적 응용의 가능성을 확대할 수 있을 것으로 기대된다.
So-Young Lee [ 이소영 | Industrial Entomology Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration, Wanju-gun, Jeollabuk-do, Korea ]
In-Woo Kim [ 김인우 | Industrial Entomology Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration, Wanju-gun, Jeollabuk-do, Korea ]
Heui-Sam Lee [ 이희삼 | Industrial Entomology Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration, Wanju-gun, Jeollabuk-do, Korea ]
Joon-Ha Lee [ 이준하 | Industrial Entomology Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration, Wanju-gun, Jeollabuk-do, Korea ]
You-Young Jo [ 조유영 | Industrial Entomology Division, Department of Agricultural Biology, National Institute of Agricultural Sciences, Rural Development Administration, Wanju-gun, Jeollabuk-do, Korea ]
Corresponding Author