Hyun Seo Lee, Se Jung Bang, Jun Gyu Paek, Da Hyeon An, Hyeon Du Jang, Ye Eun Kwon, Tae Hee Kim, Min Seok Kim, Tae Young Jang, Eun Ju Cheong, Jin Kyu Kim, Hee Kyu Kim, Sun Eun Choi
언어
영어(ENG)
URL
https://www.earticle.net/Article/A473947
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초록
영어
The Rhododendron species have traditionally been used to treat inflammation, pain, colds, and skin diseases. Some species have been reported to exhibit various biological activities, including antioxidant, anti-inflammatory, and antibacterial properties, indicating their significant potential for use as functional materials. These activities are largely attributed to the secondary metabolites found in the Rhododendron species. Notably, taxifolin-3-O-arabinopyranoside, a flavanone glycoside, has garnered attention for its various biological activities, such as antioxidant, anti-inflammatory, skin whitening, anti-wrinkle effects, and improvement of hair loss. It is increasingly recognized as a specific indicator compound for the Rhododendron species. This study conducted a chemotaxonomic screening of the 15 species of Rhododendron native to Vietnam using taxifolin-3-O-arabinopyranoside as an indicator compound. The compound was detected in samples of R. kontumense, R. maddenii, and R. triumphans through HPLC and LC-MS/MS analyses, and the highest content (26.64±4.06 ppm) was shown in the leaves of R. maddenii. On the other hand, when analyzing the roots and the branches extract of Korean R. mucronulatum, it exhibited significantly higher contents than those of the Vietnamese species, measuring 156.73±19.32 ppm and 76.87±2.60 ppm, respectively. Since the indicator compound was not detected in more than half of the Rhododendron species used in the experiment, it is suggested that the Vietnamese species may be chemically differentiated lineages. Therefore, this study provides a new perspective on the classification of the Rhododendron genus. Furthermore, this study is valuable as the first to report taxifolin-3-O-arabinopyranoside in R. kontumense, R. maddenii, and R. triumphans, and a chemotaxonomic study on the Vietnamese Rhododendron species, which has been previously insufficient.
목차
Abstract Introduction Materials and Methods Extracts and standard compound Quantitative analysis of Taxifolin-3-O-arabinopyranoside using HPLC in the Rhododendron species Confirmation of the molecular weight of Rhododendron species using LC-MS/MS Results and Discussion Conclusion Acknowledgements References
키워드
Rhododendron native to VietnamTaxifolin-3-O-arabinopyranosideHPLC analysisLC-MS/MSchemotaxonomy
저자
Hyun Seo Lee [ Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Se Jung Bang [ Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Jun Gyu Paek [ Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Da Hyeon An [ Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Hyeon Du Jang [ Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Ye Eun Kwon [ Dr. Oregonin Inc., Chuncheon 24341, Republic of Korea ]
Tae Hee Kim [ Dr. Oregonin Inc., Chuncheon 24341, Republic of Korea ]
Min Seok Kim [ Dr. Oregonin Inc., Chuncheon 24341, Republic of Korea ]
Tae Young Jang [ Department of Forest Resources, College of Forest and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Eun Ju Cheong [ Department of Forest Resources, College of Forest and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Jin Kyu Kim [ Bio Industry Department, Gyeonggi Bio-Center, Gyeonggido Business & Science Accelerator, Suwon 16229, Republic of Korea ]
Hee Kyu Kim [ Gangwon State Forest Science Institute, Chuncheon 24207, Republic of Korea ]
Sun Eun Choi [ Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University/Dr. Oregonin Inc., Chuncheon 24341, Republic of Korea ]
Corresponding Author