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Original Article

Clinical Low-Dose Computed Tomography Application for Urinary Calculi Detection Based on In Vitro Model

첫 페이지 보기
  • 발행기관
    대한방사선방어학회 바로가기
  • 간행물
    방사선방어학회지 KCI 등재 SCOPUS 바로가기
  • 통권
    VOLUME 50 NUMBER 3 (2025.09)바로가기
  • 페이지
    pp.157-164
  • 저자
    Yingdi Xie, Yangchun Gu, Jingshan Tao, Hailing Liu, Ke Zhu
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A473598

원문정보

초록

영어
Background: Low-dose computed tomography (LDCT) is gaining attention for its potential to reduce radiation exposure in clinical imaging, particularly for urinary calculi detection. However, the optimal dose and clinical efficacy of LDCT remain to be fully validated. This study aimed to identify the optimal LDCT scanning parameters using an in vitro model, then apply these findings to clinical diagnosis, and assess the efficacy of the optimal dose in detecting urinary calculi. Materials and Methods: Six distinct compositions of human urinary calculi were selected for analysis, with sizes of 1, 2, 4, and 7 mm. Stones of the same composition but different sizes were transplanted into a pork kidney, followed by computed tomography (CT) scans using decreasing doses of 120, 100, 80, 60, and 40 mAs. These scans were used to analyze the presence, size, and location of the transplanted urinary calculi. Subsequently, 150 patients with clinically suspected urinary calculi were scanned using a conventional CT dose of 120 kVp and 250 mAs, as well as the optimal low-dose parameters of 120 kVp and 60 mAs (obtained from in vitro model). Finally, the computed tomography dose index volume (CTDIvol), dose length product (DLP), and effective dose (ED) were recorded for each patient. Results and Discussion: Using the in vitro model scanning, stones of varying compositions were detected with 100% accuracy under the prescribed radiation doses. A total of 150 patients with suspected urinary calculi were included in the analysis. Both conventional-dose computed tomography (CDCT) and LDCT detected a total of 285 urinary calculi. No significant differences in image quality were observed between LDCT and CDCT (p>0.05). However, there was a substantial reduction in the CTDIvol, DLP, and ED by 81%, 79%, and 79%, respectively (p<0.05). Conclusion: LDCT shows promise in clinical practice, offering a significant reduction in radiation exposure without compromising diagnostic accuracy.

목차

ABSTRACT
Introduction
Materials and Methods
1. In Vitro Model Scanning
2. Clinical Research
Results
1. Patient Demographics
2. Stone Detection in the In Vitro Model Scan
3. Stone Diagnoses in Clinical Studies
4. Image Quality Evaluation for CDCT and LDCT
5. Radiation Dose Comparison between CDCT and LDCT
Discussion
Conclusion
Article Information
References

저자

  • Yingdi Xie [ Department of Radiology, Binhai County People’s Hospital, Yancheng, China ]
  • Yangchun Gu [ Department of Radiology, Binhai County People’s Hospital, Yancheng, China ]
  • Jingshan Tao [ Department of Radiology, Binhai County People’s Hospital, Yancheng, China ]
  • Hailing Liu [ Department of Radiology, Binhai County People’s Hospital, Yancheng, China ]
  • Ke Zhu [ Department of Radiology, Binhai County People’s Hospital, Yancheng, China ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    대한방사선방어학회 [Korean Association For Radiation Protection]
  • 설립연도
    1975
  • 분야
    자연과학>기타자연과학
  • 소개
    회원 상호간의 협조와 친목을 도모함으로써 방사선방어에 관한 제반연구 및 발전에 이바지함을 물론 학술의 국제교류 및 국제학술단체와의 상호협력 증진에 기여함을 목적으로 하며, 이 목적을 달성하기 위하여 다음 각 호의 사업을 한다. 1. 방사선방어에 관한 학술연구발표회 및 강연회 등의 개최 2. 학회지 및 방사선방어에 관한 학술간행물의 발행 및 배포 3. 방사선방어에 관한 학술의 국제교류 및 협력 4. 방사선방어에 관한 국제학술자료의 조사, 수집 및 번역 5. 방사선방어에 관한 조사 및 연구용역 6. 회원의 연구활동을 위한 제반협조 7. 기타 본 학회의 목적 달성에 필요한 사항

간행물

  • 간행물명
    방사선방어학회지 [Journal of Radiation Protection and Research]
  • 간기
    계간
  • pISSN
    2508-1888
  • 수록기간
    1976~2026
  • 등재여부
    KCI 등재,SCOPUS
  • 십진분류
    KDC 559 DDC 629

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