Earticle

초록

영어

Hepatocellular carcinoma (HCC) is a prevalent cancer with high mortality rates globally. This review explores various HCC treatments, including surgical resection, liver transplantation, local ablation, and systemic therapies. With advancements in surgical techniques, local therapies, and immunotherapy, the treatment paradigm for HCC is rapidly evolving. Surgical resection remains the preferred first-line treatment for localized HCC with preserved liver function, offering significant survival benefits. Liver transplantation is suitable for patients meeting specific criteria and helps restore liver function in individuals with compromised liver capabilities, providing excellent long-term outcomes. Local ablation is recommended for very early-stage HCC ineligible for surgery, offering outcomes comparable to resection. Transarterial therapies, such as transarterial radioembolization, are employed to treat intermediatestage HCC, enhancing treatment outcomes. Radiation therapy is increasingly utilized due to improved safety profiles, providing effective treatment options for HCC patients. Systemic treatments have advanced with the introduction of molecularly targeted therapies and immune checkpoint inhibitors, improving survival rates. The development of immunotherapy combinations has shown promising efficacy as first-line treatments. The ongoing advancement in treatment strategies, alongside personalized patient approaches, is expected to further enhance outcomes for HCC patients.

목차

Abstract 
INTRODUCTION
SURGICAL RESECTION
LIVER TRANSPLANTATION
LOCAL ABLATION
TRANSARTERIAL THERAPIES
COMBINED TREATMENT: TACE AND ADDITIONAL THERAPIES
RADIATION THERAPY
SYSTEMIC THERAPIES: CURRENT AND EMERGING TREATMENTS
1st line systemic therapy
2nd line systemic therapy
CONCLUSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES

키워드

저자

• Hyun Phil Shin [ Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea ]
• Moonhyung Lee [ Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea/Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea ]
• Jung Won Jeon [ Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613