Earticle

초록

영어

As space missions extend in duration, the impact of spaceflight on human reproduction poses serious biomedical challenges. The reproductive system is susceptible to microgravity, ionizing radiation, and circadian disruption. This review summarizes current evidence on how space environments affect reproductive function, focusing on gametogenesis, hormonal regulation, pregnancy, and embryonic development. We reviewed data from rodent models, parabolic flight experiments, and space-exposed cellular systems to assess the effect of space-relevant stressors on reproductive health. Findings show that microgravity impairs sperm motility and hormonal balance, while radiation increases DNA fragmentation and induces heritable epigenetic changes. Female reproductive health is similarly affected, with radiation accelerating follicular loss and hormonal disruption impairing ovulation. Early pregnancy stages, including implantation and placental development, are especially vulnerable to space conditions. Rodent studies indicate that while basic fertility may persist, the long-term effect on offspring health and multi-generational outcomes remains unclear. These findings highlight the need for targeted countermeasures and continued research to ensure reproductive success in future space missions.

목차

ABSTRACT
INTRODUCTION
MAIN BODY
Effects of spaceflight on the male reproductive system
Effects of spaceflight on female reproductive system
Pregnancy and embryonic development in space
Future direction for research
CONCLUSION
REFERENCES

키워드

저자

• Byeonggyu Ahn [ Department of Physiology, College of Medicine and Institute of Medical Sciences, Gyeongsang National University/Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea ]
• Jina Ha [ Department of Physiology, College of Medicine and Institute of Medical Sciences, Gyeongsang National University/Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea ]
• Dawon Kang [ Department of Physiology, College of Medicine and Institute of Medical Sciences, Gyeongsang National University/Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea ] Corresponding Author

참고문헌

발행기관

간행물

관심저널 등록

• 간행물명

  Journal of Animal Reproduction and Biotechnology

• 간기

  계간

• pISSN

  2671-4639

• eISSN

  2671-4663

• 수록기간

  2019~2026

• 십진분류

  KDC 527 DDC 636