Earticle

초록

영어

This research explores the mechanical behavior of whole blood as a shear-thinning fluid and examines yield stress as a crucial parameter for evaluating flow properties in the microvasculature. While previous studies have primarily focused on whole blood viscosity (WBV), this study presents an engineering-based approach to quantitatively evaluate the yield stress of non-Newtonian whole blood using a U-shaped capillary tube. A custom-designed scanning capillary tube, incorporating a biocompatible U-shaped capillary channel, was employed to determine whole blood viscosity (WBV) across shear rates from 1 to 1,000 s⁻1. Yield stress was estimated by extrapolating the shear stress-shear rate relationship using a non-Newtonian shear-thinning flow model. The analysis revealed a strong cubic correlation between hematocrit and yield stress, suggesting an increased risk of flow impairment in the microvasculature with elevated hematocrit levels. This work emphasizes the critical influence of yield stress in regulating microvascular blood flow, particularly under low-shear conditions.

목차

Abstract
1. Introduction
2. Materials and Methods
2.1 A biocompatible U-shaped tube with capillary channel
2.2 Determination of WBV and yield stress
2.3 Sample preparation and analytical procedure
3. Results and Discussion
3.1 Viscosity comparison
3.2 Relationship between hematocrit and yield stress
4. Conclusion
Declaration of Interests
Acknowledgement
References

키워드

저자

• 정진무 [ Jinmu Jung | Department of Mechanical Design Engineering, College of Engineering, Jeonbuk National University/ Hemorheology Research Institute, Jeonbuk National University ]
• 권덕철 [ Deok-Cheol Kwon | Industry-Academic Cooperation Office, Jeonbuk National University ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국기계항공기술학회지(구 한국기계기술학회지) [Journal of the Korean Society of Mechanical and Aviation Technology ]

• 간기

  격월간

• pISSN

  1229-604X

• eISSN

  2508-3805

• 수록기간

  1999~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 550 DDC 620