Exercise and rehabilitation interventions are essential for health resto-ration, yet reviews on related clinical trials remain limited despite in-creasing research interest. This study analyzed the characteristics, de-signs, sample sizes, and outcome variables of clinical trials registered with the Clinical Research Information Service in South Korea, focusing on exercise and rehabilitation interventions. A systematic search using “exercise” and “rehabilitation” identified 1,089 trials registered up to June 9, 2024, with 470 meeting the inclusion criteria. Most studies (79.79%) were retrospectively registered, and 45.11% were open-label trials. Behavioral interventions (26.60%) and medical devices (22.34%) were most common, targeting circulatory (27.45%) and musculoskeletal (19.79%) conditions. Frequently assessed outcomes included ‘balance,’ ‘pain,’ and ‘walking.’ A notable increase in trials was observed since 2017. However, the high proportion of retrospective registrations and open-label designs highlights the need for more prospective and blind-ed trials to enhance research quality.
목차
Abstract INTRODUCTION MATERIALS AND METHODS Search strategy for the CRIS database Inclusion and exclusion criteria Data collection Data analysis RESULTS Study selection process Annual trends in clinical trial registrations Characteristics and design of the studies Analysis of outcome variables DISCUSSION CONFLICT OF INTEREST ACKNOWLEDGMENTS REFERENCES
키워드
ExerciseRehabilitationInterventionClinical trialClinical research
저자
Jae-Hyun Lim [ Department of Physical Therapy, Graduate School, Nambu University, Gwangju, Korea ]
Byeong-Geun Kim [ Department of Physical Therapy, Nambu University, Gwangju, Korea ]
Ah-Young Choi [ Department of Rehabilitation, Songwon University, Gwangju, Korea ]
Corresponding Author