The physical and optical properties of functional hydrogel lenses manufactured using Gallate and Carotenoid group materials as additives for hydrogel lenses were analyzed. In order to manufacture a hydrogel lens, a hydrophilic monomer, HEMA (2-hydroxyethyl methacrylate), a cross-linker EGDMA (ethylene glycol dimethacrylate), and a photoinitiator 2H2M (2-hydroxy-2-methylpropyphenone) were used. Additives such as Epigallocatechin gallate, Octyl gallate, and Astaxanthin were added to the basic mixed solution at a ratio, respectively, and photopolymerized with a wavelength of 365 nm for 40 seconds by a cast mold method. The Carotenoid material produced a nano dispersion through the solvent substitution method, and the physical properties of the manufactured contact lens were evaluated by measuring refractive index, water content, spectral transmittance, and contact angle to analyze the changes in physical properties according to the material. Hydrogel contact lenses using the gallate group showed increased wettability and high UV blocking ability compared to base hydrogel lenses. In addition, lenses with epigallocatechin gallate added produced a gradually darker pink color as the amount added increased. Hydrogel lenses using carotenoid nano dispersions showed an increase in both refractive index and water content, and a tendency toward higher wettability. In addition, contact lenses manufactured using an optimized blending ratio of gallate and carotenoid showed increased refractive index, water content, and wettability, as well as antibacterial function and improved UV blocking ability. Hydrogel lenses are manufactured by adding gallate and carotenoid to basic lens material in the ratio can be used as functional medical eye materials with high refractive index, water content, wettability, UV blocking properties, and antibacterial properties.
목차
Abstract 1. Introduction 2. Materials and Methods 2.1. Reagents and Materials 2.2. Experimental method 2.3. Instruments and analysis 3. Results and Discussions 3.1. Characteristics of hydrogel with gallate group 3.2. Characteristics of hydrogel with carotenoid group 3.3. Characteristics of hydrogel using a combination of gallate and carotenoid 4. Conclusion References
키워드
CarotenoidGallateFunctional contact lensesOphthalmic medical useUV protection
저자
Seong Hoon Bang [ Department of Optometry & Vision Science, Daegu Catholic University ]
A-Young Sung [ Department of Optometry & Vision Science, Daegu Catholic University ]
Corresponding Author
조선대학교 기초과학연구원 [The Natural Science Research Institute of Chosun]
설립연도
2008
분야
자연과학>자연과학일반
소개
본 연구원은 기초과학을 진흥하기 위한 연구·교육 및 그 보급을 목적으로 한다. 이 목적을 달성하기 위하여 다음 각 호의 사업을 수행한다.
1. 기초과학 제 분야에 관한 조사와 연구
2. 기초과학에 관한 학술행사(학술대회, 학술세미나, 심포지엄, 초청강연회 등) 개최
3. 학문후속세대 및 일반인을 위한 기초과학 교육
4. 기관지『조선자연과학논문지』 발간
5. 『자연과학연구총서』, 『자연과학번역총서』 등 단행본 발간
6. 기타 본 연구원의 목적과 관련된 사업
간행물
간행물명
통합자연과학논문집(구 조선자연과학논문집) [Journal of Integrative Natural Science]