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The Antihyperlipidemic Effect of Fried Chicken Mushroom (Lyophyllum decastes) in Hyperlipidemic Rats induced by High Fat and Cholesterol Diet.

첫 페이지 보기
  • 발행기관
    한국버섯학회 바로가기
  • 간행물
    버섯 바로가기
  • 통권
    제28권 2호 통권 49호 (2024.10)바로가기
  • 페이지
    pp.21-21
  • 저자
    Tae Soo Lee, Min Woong Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A457485

원문정보

초록

영어
This study was aimed to investigate the dietary supplementation with the fruiting body of Lyophyllum decastes (LD) mushroom on body weight, plasma lipid profiles and histopathological changes of the liver in rats fed a high-fat and high-cholesterol diet. Five-week-old female Sprague-Dawley albino rats were divided into four groups, each consisting of eight: a normal control diet (NC group), an high-fat and hhigh-cholesterol diet (HFC group), an HFC diet supplemented with 0.03% simvastatin (HFC+SS group) and an HFC diet supplemented with 5% fruiting body powder of Lyophyllum decastes (HFC+LD group). In the HFC+LD group, plasma total cholesterol (TC), low density lipoprotein (LDL-C), and triglyceride (TG) concentrations were significantly lower than those in the HFC group. Additionally, body weight gain in the HFC+LD group was lower compared to the HFC group. No adverse effects were observed in the levels of plasma albumin, creatinine, blood urea nitrogen, uric acid, glucose, and total protein in the HFC+LD group. Enzyme activities related to liver function, such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT), were similar to those in other groups including NC, HFC, HFC+SS and HFC+LD. Feeding the rats with HFC diet supplemented with mushroom powder (HFC+LD group) increased the excretion of total lipid and total cholesterol compared to HFC group in the feces. Histopathological analysis revealed that the HFC group developed hepatic steatosis, while the HFC+DL group showed only minimal fat droplets in the liver tissues. In conclusion, the results suggested that an HFC diet supplemented with 5% fruiting body powder of LD provides health benefits to rats by acting on lowering atherogenic lipid profiles and body weights.

키워드

Antilipidemia anti-obesity Lipid profiles Lyophyllum decastes steatosis

저자

  • Tae Soo Lee [ Division of Life Sciences, Incheon National University, Incheon 22012, Republic of Korea ]
  • Min Woong Lee [ Department of Biology, Dongguk University, Seoul 04620, Republic of Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국버섯학회 [The Korean Society of Mushroom Science]
  • 설립연도
    1997
  • 분야
    농수해양>농학
  • 소개
    우리나라의 버섯 연구와 관련 산업의 발전에 기여하고 버섯관련 연구자와 관련산업 종사자간의 학술정보 등의 교류를 목적으로 한다.

간행물

  • 간행물명
    버섯 [Mushroom]
  • 간기
    반년간
  • 수록기간
    1997~2025
  • 십진분류
    KDC 525 DDC 635

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