2021 International Symposium of Institute of Forest Science (2021.10)바로가기
페이지
pp.16-16
저자
Fanyu Zhao, Jin-Chul Kim
언어
영어(ENG)
URL
https://www.earticle.net/Article/A450402
원문정보
초록
영어
Dipalmitoylphosphatidylcholine (DPPC) liposome was surface-decorated with hydrophobically modified thiolated carboxymethylcellulose (Hm TL-CMC)-capped gold nanoparticle (GNP) and hydrophobically modified poly(N-isopropylacrylamide) (Hm PNIPAM). GNP was prepared using Hm TL-CMC as a reducing agent for gold ions and a capping material for GNP. DPPC liposomes incorporating Hm TL-CMC-capped GNP and Hm PNIPAM were prepared by a film hydration and sonication method and they exhibited a multi lamellar structure along with GNP on its TEM micrograph. The temperature-responsive release of DPPC liposome was promoted when the liposome was incorporating Hm PNIPAM, possibly due to the thermal contraction of the polymer chains. DPPC liposome incorporating Hm TL-CMC-capped GNP showed a NIR-responsive release, possibly due to the photo thermal effect of GNP, and the NIR-responsive release was enhanced when the liposome was bearing Hm PNIPAM.
Fanyu Zhao [ Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Jin-Chul Kim [ Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Corresponding Author