Earticle

초록

영어

Gynura procumbens (Lour.) Merr. is one of the Gynura species commonly known as ‘Sambung Nyawa’ in Malay and as ‘bai bing cao’ in China, where it is traditionally used to treat various health ailments such as eruptive fevers, rash, kidney disease, migraines, constipation, hypertension, diabetes mellitus, and cancer. Recently, pharmacologic studies reported that G. procumbens has anti-oxidant, anti–Herpes simplex virus, anti–hyperglycemic, anti–hyperlipidemic, anti–inflammatory, analgesic, and reduced blood hypertension properties. Today, people in various tropical regions consume an increasing amount of G. procumbens leaves in diet and tea, and research shows that leaves contents are not having any toxic effects. The health benefits of consuming G. procumbens are related to the amount of bioactive compounds found in it, such as flavonoids, tannins, saponins, terpenes, and alkaloids but available literature indicates that little previous studies of secondary metabolites have been done on G. procumbens roots after picking leaves from G. procumbens. In this work, the constituents of the root of G. procumbens were isolated by column chromatography on silica gel, Sephadex LH-20 and recrystallization. Their structures were elucidated by physicochemical properties and spectral analysis. ceramides,N-((5E,8R,11E)-1,8-dihydroxyheptadeca-5,11-dien-1-yl)-2-hydroxypentacosan amide (1), together with three known steroidal compounds, β-sitosterol (1), daucosterol (2), and stigmasterol (3) was isolated. The structure of the new compound was determined based on spectroscopic methods including 1D and 2D NMR and MS spectrometry. The stereochemistry was determined by NOESY experiments.

키워드

저자

• Lei Wu [ Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330029, P.R. China; Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science & Technology, Tianjin 300457, P.R. China ]
• Wei Xiong [ Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330029, P.R. China ]
• Ju-Wu Hu [ Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330029, P.R. China ]
• Xiong-Hui Li [ Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330029, P.R. China ]
• Gang Xu [ Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330029, P.R. China ] Corresponding Author
• Young-Soo Bae [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]

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• 간행물명

  강원대학교 산림과학연구소 학술대회

• 간기

  부정기

• 수록기간

  2017~2024

• 십진분류

  KDC 526 DDC 634