Earticle

초록

영어

Background: We investigated the impact of 0.35 T magnetic field on dose calculation for nonsmall cell lung cancer (NSCLC) stereotactic ablative radiotherapy (SABR) in the ViewRay system (ViewRay Inc.), which features a simultaneous use of magnetic resonance imaging (MRI) to guide radiotherapy for an improved targeting of tumors. Materials and Methods: Here, we present a comprehensive analysis of the effects induced by the 0.35 T magnetic field on various characteristics of SABR plans including the plan qualities and dose calculation for the planning target volume, organs at risk, and outer/inner shells. Therefore, two SABR plans were set up, one with a 0.35 T magnetic field applied during radiotherapy and another in the absence of the field. The dosimetric parameters were calculated in both cases, and the plan quality indices were evaluated using a Monte Carlo algorithm based on a treatment planning system. Results and Discussion: Our findings showed no significant impact on dose calculation under the 0.35 T magnetic field for all analyzed parameters. Nonetheless, a significant enhancement in the dose was calculated on the skin surrounding the tumor when the 0.35 T magnetic field was applied during the radiotherapy. This was attributed to the electron return effect, which results from the deviation of the electrons ejected from tissues upon radiation due to Lorentz forces. These returned electrons re-enter the tissues, causing a local dose increase in the calculated dose. Conclusion: The present study highlights the impact of the 0.35 T magnetic field used for MRI in the ViewRay system for NSCLC SABR treatment, especially on the skin surrounding the tumors.

목차

ABSTRACT
Introduction
Materials and Methods
1. Patient Selection
2. Treatment System (ViewRay)
3. SABR Plans for Lung Cancer
4. Statistics Analysis
5. Plan Evaluation
Results and Discussion
1. PTV Dose Distribution Difference
2. Plan Qualities Difference
3. Organs at Risk Dose Distribution Difference
4. Dose Distribution Difference around the Skin
Conclusion
Conflict of Interest
Acknowledgements
Ethical Statement
Author Contribution
References

키워드

저자

• Jaeman Son [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea ]
• Sung Young Lee [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea ]
• Chang Heon Choi [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea ]
• Jong Min Park [ Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea ]
• Jung-in Kim [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629