Earticle

초록

영어

Phytolacca has been used as food and folk medicines for rheumatism and arthritis in America and East Asia. All parts of it can be considered toxic unless it is properly prepared. Some acute intoxication cases occurred by taking Phytolacca without proper treatment, or accidently misusing it as edible roots. Poisoning by Phytolacca can cause minor digestive trouble such as vomiting, abdominal cramps and diarrhea. But in some cases, it can result serious symptoms like seizures, acute kidney failure and even death. The roots of Phytolacca are similar to other edible roots, so they can be mistakenly ingested. In this study, we presented a fatal post-mortem intoxication case of Phytolacca poisoning. The heart and peripheral blood, gastric contents were collected from autopsy, and the ingested plant roots from the scene submitted for toxicological analysis. The detection of triterpenoid saponins in biological samples and plant materials were performed by solid-phase extraction (SPE) followed by liquid chromatography-mass spectrometry (LC-MS/MS). The concentrations of esculentoside A in the heart and peripheral blood were 37 ng/mL and 27 ng/mL, respectively, while those of esculentoside H were 3 ng/mL and 1 ng/mL, respectively.

목차

Abstract
Ⅰ. 서론
Ⅱ. 재료 및 방법
1. 사건 개요
2. 시약 및 재료
3. 시료 전처리
4. LC-MS/MS 조건
Ⅲ. 결과 및 고찰
Ⅳ. 사사
Ⅴ. 참고문헌

키워드

저자

• 김병주 [ Byungjoo Kim | 서울과학수사연구소 독성화학과 ]
• 문성민 [ Sungmin Moon | 서울과학수사연구소 독성화학과 ]
• 김정현 [ Junghyun Kim | 서울과학수사연구소 독성화학과 ]
• 김소현 [ Sohyun Kim | 서울과학수사연구소 독성화학과 ]
• 강민지 [ Minji Kang | 서울과학수사연구소 독성화학과 ]
• 박미정 [ Meejung Park | 서울과학수사연구소 독성화학과 ]
• 최혜영 [ Hyeyoung Choi | 서울과학수사연구소 독성화학과 ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국법과학회지 [Korean Journal of Forensic Science]

• 간기

  반년간

• pISSN

  1598-0715

• 수록기간

  2000~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 367 DDC 347