Earticle

초록

영어

LSD (Lysergic acid diethylamide) is a widely used recreational drug usually take at around 100 mcg for extremely potent hallucinogenic effect. It first synthesized in 1938, synthetically made from lysergic acid. ALD-52, prodrug of LSD, was abused in various forms such as blotter paper, tablet or diluted as a liquid and the characteristic hallucinogenic effects of ALD-52 that stimulating pleasurable and mind-altering or an unpleasant, sometimes terrifying experience of LSD is via interaction with the serotonin receptors. The physical effects of ALD-52 distorted visual perception of shapes and colors, altered sounds, anxiety, depression, rapid increased heart rate, increased body temperature, high blood pressure, and diluted pupils. Experience flashback can last days or even months after taking the last dose and occurs suddenly, may also manifest relatively long-lasting psychoses such as schizophrenia or severe depression. Under the influence of ALD-52, the ability to make sensible judgements and see common dangers in impaired making the user susceptible to personal injury or death. Structure of ALD-52 is in which an acetyl group is added to the LSD. The molecule weight of ALD-52 is 365.210, major ions are m/z 365.3, 263.1, and 72.1, retention time is 20.37 min at GC-MSD. From the LC-QTOF results, specific MSMS fragmentations of 265.1326, 223.1217, 323.1746, and 366.2173 (M+H) of ALD-52 were confirmed.

목차

Abstract
Ⅰ. Introduction
Ⅱ. Materials and Methods
1. Reagents and ingredients
2. Equipment
3. Sample preparation
Ⅲ. Results and discussions
Ⅳ. Conclusion
Ⅴ. Acknowledgements
Ⅵ. References

키워드

저자

• Heesang Lee [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ] Corresponding author
• Jaeook Kim [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ]
• Ho-Sun Lee [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ]
• Young-Hoon Jo [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ]
• Jung-Ah Ko [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ]
• Sanghwan In [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ]
• Joon-Bae Lee [ Forensic Toxicology and Chemistry Division, Daegu Institute, National Forensic Service, Chilgok, Korea ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국법과학회지 [Korean Journal of Forensic Science]

• 간기

  반년간

• pISSN

  1598-0715

• 수록기간

  2000~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 367 DDC 347