Earticle

초록

영어

Background: The hemi-body electron beam irradiation (HBIe–) technique has been proposed for the treatment of mycosis fungoides. It spares healthy skin using an electron shield. However, shielding electrons is complicated owing to electron scattering effects. In this study, we developed a thimble-like head bolus shield that surrounds the patient’s entire head to prevent irradiation of the head during HBIe–. Materials and Methods: The feasibility of a thimble-like head bolus shield was evaluated using a simplified Geant4 Monte Carlo (MC) simulation. Subsequently, the head bolus was manufactured using a three-dimensional (3D) printed mold and Ecoflex 00-30 silicone. The fabricated head bolus was experimentally validated by measuring the dose to the Rando phantom using a metal-oxide-semiconductor field-effect transistor (MOSFET) detector with clinical configuration of HBIe–. Results and Discussion: The thimble-like head bolus reduced the electron fluence by 2% compared with that without a shield in the MC simulations. In addition, an improvement in fluence degradation outside the head shield was observed. In the experimental validation using the inhouse- developed bolus shield, this head bolus reduced the electron dose to approximately 2.5% of the prescribed dose. Conclusion: A thimble-like head bolus shield for the HBIe– technique was developed and validated in this study. This bolus effectively spares healthy skin without underdosage in the region of the target skin in HBIe–.

목차

ABSTRACT
Introduction
Materials and Methods
1. Monte Carlo Simulation
2. Experimental Configuration
Results and Discussion
Conclusion
Conflicts of Interest
Acknowledgements
Author Contribution
References

키워드

저자

• Wook-Geun Shin [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, ]
• Sung Young Lee [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea ]
• Hyeongmin Jin [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, Korea ]
• Jeongho Kim [ Department of Radiation Oncology Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea ]
• Seonghee Kang [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, Korea ]
• Jung-in Kim [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, Korea ]
• Seongmoon Jung [ Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea; Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629