TaeHee Kim, Ye Eun Kwon, Sun Min Park, Min Seok Kim, Young Hwan Jeong, Se Yeong Park, Young-Soo Bae, Eun Ju Cheong, Yi-Chang He, Chun Gong, Wei Gao, Hee Kyu Kim, Yeon Ho Ham, Jin-Kyu Kim, Sun Eun Choi
언어
영어(ENG)
URL
https://www.earticle.net/Article/A417781
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원문정보
초록
영어
Genus of Rhododendron has been used in traditional medicine since ancient times and is known to be effective in immune function, inflammation, and cold symptoms. And the reason for this activity is the flavanonol type among flavonoids in the genus of Rhododendron. Among the flavanonol types, Taxifolin-3-O-arabinopyranoside was isolated from the root of native R. mucronulatum in Korea, and the structure was finally identified through HPLC, LC-MS/MS, 1H-NMR, and 13C-NMR. Taxifolin-3-O-arabinopyranoside is a compound mainly found in R. mucronulatum, a representative species of the genus of Rhododendron, and exhibits antioxidant, anti-inflammatory, and anti-atopic activities. In this study, Taxifolin-3-O-arabinopyranoside was chemotaxonomic significant in 5 species of the genus Rhododendron native to Korea (R. mucronulatum, R. mucronulatum var. ciliatum, R. schlippenbachii, R. yedoense var. Poukhanense, R. japonicum for. Flavum). Compared with the existing literature, Taxifolin-3-O-arabinopyranoside was identified for the first time in 4 species of Rhododendron except for the R. mucronulatum.
목차
Abstract Introduction Materials and Methods Plant extracts of Rhododendron species Separation of active compounds in the root of R.mucronulatum Structural identification of active compound isolated from an extract of the root of R. mucronulatum Quantitative analysis of Taxifolin-3-O-arabinopyranoside using HPLC of several species of the genus of Rhododendron Molecular weight confirmation using LC-MS/MS of several species of the genus of Rhododendron Results and Discussion Conclusion Acknowledgements References
키워드
Rhododendron specieschemotaxonomyNMRLC-MS/MSHPLC
저자
TaeHee Kim [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Ye Eun Kwon [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Sun Min Park [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Min Seok Kim [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Young Hwan Jeong [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Se Yeong Park [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Young-Soo Bae [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Eun Ju Cheong [ College of Forest and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Yi-Chang He [ Jiangxi Academy of Forestry, Jiangxi Province, Nanchang 330032, China ]
Chun Gong [ Jiangxi Academy of Forestry, Jiangxi Province, Nanchang 330032, China ]
Wei Gao [ Jiangxi Academy of Forestry, Jiangxi Province, Nanchang 330032, China ]
Hee Kyu Kim [ Gangwondo Forest Science Institute, Chuncheon 24207, Republic of Korea ]
Yeon Ho Ham [ Gangwondo Forest Science Institute, Chuncheon 24207, Republic of Korea ]
Jin-Kyu Kim [ Gyeonggido Business and Science Accelerator, Suwon 16229, Republic of Korea ]
Sun Eun Choi [ Department of Forest Biomaterials Engineering, College of Forest & Environmental Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea ]
Corresponding author