This study was carried out to evaluate sensitivity, specificity, and test cutoff score to predict cardiorespiratory fitness by using the 2-min step test (2MST) in patients with type 2 diabetes mellites (DM). The associa-tion of the 2MST and physical fitness tests including a 6-min walk test (6MWT), a 5 time sit-to-stand test (FTSST), and leg strength in the form of a leg performance test were also investigated. This study was cross-sectional and conducted in 100 type 2 DM patients. Patients were screened through health questionnaires, medical illness, general char-acteristics, and physical fitness tests; 2MST, 6MWT, FTSST, and leg strength. Blood was collected for assessment of fasting blood sugar and lipid profiles. The number of steps in the 2MST was positively cor-related with the distance of the 6MWT (r=0.6995, P<0.0001) and leg strength (r=0.4292, P<0.0001). 2MST was negatively correlated with time to perform the FTSST (r=-0.405, P<0.0001). Moreover, this study established the optimal cutoff score of the 2MST at ≤61 steps with 92.24% sensitivity, and 81.36% specificity to predict cardiorespiratory fitness in type 2 DM patients. Our findings indicate that the 2MST may be used as a predictor for walking capacity, leg strength, and ability to change position from sitting to standing in type 2 DM. In addition, this result may imply that patients with type 2 DM performing the 2MST at less than 61 steps was significantly associated with decreased cardio-respiratory fitness.
목차
Abstract INTRODUCTION MATERIALS AND METHODS Study designs and participants Study protocols 5 Time sit-to-stand test 2-Min step test Leg strength test 6-Min walk test Statistical analysis RESULTS General characters of all participants Comparative effects between 6MWT and 2MST on physiological changes, dyspnea, and leg fatigue in type2 DM participants The correlation between 2-min step test and physical fitness tests in all DM participants The correlation between 2-min step test, age, height, and body weight in all DM participants The optimal cutoff score, sensitivity, specificity, and AUC of the 2-min step test in all type 2 DM participants. DISCUSSION CONFLICT OF INTEREST ACKNOWLEDGMENTS REFERENCES
Arunrat Srithawong [ Department of Physical Therapy, School of Allied Health Sciences, University of Phayao, Phayao, Thailand, Unit of Excellent of Physical Fitness and Exercise, University of Phayao, Phayao, Thailand ]
Puttipong Poncumhak [ Department of Physical Therapy, School of Allied Health Sciences, University of Phayao, Phayao, Thailand, Unit of Excellent of Physical Fitness and Exercise, University of Phayao, Phayao, Thailand ]
Pacharee Manoy [ Department of Physical Therapy, School of Allied Health Sciences, University of Phayao, Phayao, Thailand, Unit of Excellent of Physical Fitness and Exercise, University of Phayao, Phayao, Thailand ]
Sirintip Kumfu [ Department of Physical Therapy, School of Allied Health Sciences, University of Phayao, Phayao, Thailand, Unit of Excellent of Physical Fitness and Exercise, University of Phayao, Phayao, Thailand ]
Tichanon Promsrisuk [ Unit of Excellent of Physical Fitness and Exercise, University of Phayao, Phayao, Thailand, Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand ]
Piyapong Prasertsri [ Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand, Exercise and Nutrition Innovation and Sciences Research Unit, Burapha University, Chonburi, Thailand ]
Orachorn Boonla [ Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand, Exercise and Nutrition Innovation and Sciences Research Unit, Burapha University, Chonburi, Thailand ]
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