Earticle

초록

영어

Background: A comprehensive, traceable, and easy-to-understand radiation risk indicator is desired for radiological protection. The early-onset hypothesis could be used for this purpose. Materials and Methods: An indicator for early death (IED) was developed and calculated using the epidemiological dataset from the 14th Report of the Life Span Study (LSS) of Hiroshima and Nagasaki. By clarifying the calculation process, IED for all-cause mortality was estimated. In addition, the characteristics of IED for solid cancer mortality and cardiovascular mortality as well as those of men and women, and their dependence on age at exposure were investigated for detailed analysis. Results and Discussion: The IED for all-cause mortality was estimated to be approximately 4 years for an acute radiation exposure of 1 Gy regardless of the fitting dose range. The cumulative death rate for all solid cancers also indicated the early-death tendency (approximately 7– 10 years at 1 Gy). Although, there is a slight difference in the characteristics of the risk obtained from the LSS study and this study, it is considered that the IED in a unit of years can also be used to show the overall picture of risk due to radiation exposure. Conclusion: We developed and calculated the indicator for early death, IED, for the cumulative mortality rate of all causes of death, all solid cancers, and circulatory diseases. The quantitative values of IED were estimated to be 4 years for all causes of death, 7–10 years for all solid cancers. IED has an advantage for intuitively understanding the meaning of radiation risk since it can be obtained by a simple and traceable method.

목차

ABSTRACT
Introduction
Materials and Methods
1. Epidemiological Data
2. Calculation of the IED
3. Different Endpoints and Additional Detailed Analysis
Results and Discussion
1. Cumulative Death Rate and Fitting for Reference Case and Other Dose Categories
2. Cumulative Death Rates for All Solid Cancers and Circulatory Diseases
3. Dependences of Cumulative Death Rate on Age at Exposure and Sex
4. Comparison with Risk Estimates from LSS Data
5. Limitation and Advantages of IED
Conclusion
Conflict of Interest
Acknowledgements
Author Contribution
References

키워드

저자

• Michiya Sasaki [ Central Research Institute of Electric Power Industry, Tokyo, Japan ] Corresponding Author
• Yuki Fujimichi [ Central Research Institute of Electric Power Industry, Tokyo, Japan ]
• Kazuo Yoshida [ Central Research Institute of Electric Power Industry, Tokyo, Japan ]
• Toshiyasu Iwasaki [ Central Research Institute of Electric Power Industry, Tokyo, Japan ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  방사선방어학회지 [Journal of Radiation Protection and Research]

• 간기

  계간

• pISSN

  2508-1888

• 수록기간

  1976~2026

• 등재여부

  KCI 등재,SCOPUS

• 십진분류

  KDC 559 DDC 629