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The theranostic roles of extracellular vesicles in pregnancy disorders

첫 페이지 보기
  • 발행기관
    한국동물생명공학회(구 한국동물번식학회) 바로가기
  • 간행물
    Journal of Animal Reproduction and Biotechnology 바로가기
  • 통권
    Volume. 37 No. 1 (2022.03)바로가기
  • 페이지
    pp.2-12
  • 저자
    Islam M. Saadeldin, Bereket Molla Tanga, Seonggyu Bang, Xun Fang, Ki-Young Yoon, Sanghoon Lee, Jongki Cho
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A410034

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원문정보

초록

영어
Extracellular vesicles (EVs) are nanovesicles that carry bioactive cargoes of proteins, lipids, mRNAs, and miRNAs between living cells. Their role in cellular communication has gained the attention of several research reports globally in the last decade. EVs are critically involved in sperm functions, oocyte functions, fertilization, embryonic development, and pregnancy. The review summarizes the state-of-theart of EVs research in the diagnostic and therapeutic (theranostic) potentials of the EVs during the pregnancy that might provide a solution for gestational disturbances such as implantation failure, maternal health problems, gestational diabetes, and preeclampsia. EVs can be found in all biological fluids of the fetus and the mother and would provide a non-invasive and excellent tool for diagnostic purposes. Moreover, we provide the current efforts in manufacturing and designing targeted therapeutics using synthetic and semi-synthetic nanovesicles mimicking the natural EVs for efficient drug delivery during pregnancy.

목차

ABSTRACT
INTRODUCTION
Role of EVs in implantation and pregnancy
Diagnostic roles for female infertility and pregnancy disorders
Therapeutic roles of synthetic and semi-synthetic exosomes for female infertility and pregnancy
CONCLUDING REMARKS AND FUTURE PERSPECTIVES
REFERENCES

키워드

diagnosis extracellular vesicles placenta pregnancy therapy

저자

  • Islam M. Saadeldin [ Lab. of Theriogenology, College of Veterinary Medicine, Chungnam National University, Research Institute of Veterinary Medicine, Chungnam National University, Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt ]
  • Bereket Molla Tanga [ Lab. of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea ]
  • Seonggyu Bang [ Lab. of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea ]
  • Xun Fang [ Lab. of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea ]
  • Ki-Young Yoon [ Department of Companion Animal, Shingu College, Seongnam 13174, Korea ]
  • Sanghoon Lee [ Lab. of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea ]
  • Jongki Cho [ Lab. of Theriogenology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국동물생명공학회(구 한국동물번식학회) [The Korean Society of Animal Reproduction and Biotechnology]
  • 설립연도
    1976
  • 분야
    농수해양>축산학
  • 소개
    동물번식생리학, 동물생명공학, 수의학, 인공수정 및 수정란이식을 이용한 동물개량에 관한 이론과 기술의 발전을 통해 학계, 연구계, 산업계 및 양축가 상호간의 협력을 도모함으로써 동물과학발전 및 사회일반의 이익에 기여 한다는 목적을 위해 노력해 나가겠습니다.

간행물

  • 간행물명
    Journal of Animal Reproduction and Biotechnology
  • 간기
    계간
  • pISSN
    2671-4639
  • eISSN
    2671-4663
  • 수록기간
    2019~2025
  • 십진분류
    KDC 527 DDC 636

이 권호 내 다른 논문 / Journal of Animal Reproduction and Biotechnology Volume. 37 No. 1

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