Earticle

초록

영어

A decline in estrogen levels during menopause is associated with the loss of muscle mass and function, and it can accelerate sarcopenia. However, with the growing number of postmenopausal women due to the increase in life expectancy, the effects of estrogen on skeletal mus-cle are not completely understood. This article reviews the relationship between estrogen deficiency and skeletal muscle, its potential mecha-nisms, including those involving mitochondria, and the effects of exer-cise on estrogen deficiency-induced skeletal muscle impairment. In particular, mitochondrial dysfunction induced by estrogen deficiency accelerates sarcopenia via mitochondrial dynamics, mitophagy, and mitochondrial-mediated apoptosis. It is well known that exercise train-ing is essential for health, including for the improvement of sarcopenia. This review highlights the importance of exercise training (aerobic and resistance exercise) as a therapeutic intervention against estrogen de-ficiency-induced sarcopenia.

목차

Abstract
INTRODUCTION
SARCOPENIA AND MENOPAUSE
ESTROGEN AND THE SKELETAL MUSCLE
ESTROGEN AND MITOCHONDRIA IN THE SKELETAL MUSCLE
EFFECTS OF EXERCISE ON THE SKELETAL MUSCLE IN ESTROGEN DEFICIENCY
CONCLUSIONS
ACKNOWLEDGMENTS
REFERENCES

키워드

저자

• Eun-Jeong Cho [ Department of Biomedical Science, Program in Biomedical Science and Engineering, Inha University, Incheon, Korea ]
• Youngju Choi [ Institute of Sports & Arts Convergence, Inha University, Incheon, Korea ]
• Su-Jeen Jung [ Department of Leisure Sports, Seoil University, Seoul, Korea ]
• Hyo-Bum Kwak [ Department of Biomedical Science, Program in Biomedical Science and Engineering, Inha University, Incheon, Korea, Institute of Sports & Arts Convergence, Inha University, Incheon, Korea ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  JER [Journal of Exercise Rehabilitation]

• 간기

  격월간

• pISSN

  2288-176X

• eISSN

  2288-1778

• 수록기간

  2013~2026

• 등재여부

  SCOPUS,KCI 등재

• 십진분류

  KDC 517 DDC 613