Earticle

초록

영어

Mutations in the luteinizing hormone/chorionic gonadotropin receptors (LH/CGRs), representatives of the G protein-coupled receptor family, have been rapidly identified over the last 20 years. This review aims to compare and analyze the data reported the activating and inactivating mutations of the LH/CGRs between human, rat, equine and fish, specifically (Japanese eel Anguilla japonica). Insights obtained through detailed study of these naturally-occurring mutations provide a further update of structure-function relationship of these receptors. Specifically, we present a variety of data on eel LH/CGR. These results provide important information about LH/CGR function in fish and the regulation of mutations of the highly conserved amino acids in glycoprotein hormone receptors.

목차

ABSTRACT
INTRODUCTION
Activating mutations
Inactivating mutations
SUMMARY AND PERSPECTIVE
REFERENCES

키워드

저자

• Kwan-Sik Min [ Institute of Genetic Engineering, Hankyong National University, Department of Animal Biotechnology, Graduate School of Hankyong National University, Department of Animal Life Science, Hankyong National University, Ansung 17579, Korea ] Corresponding Author
• Munkhzaya Byambaragchaa [ Institute of Genetic Engineering, Hankyong National University, Ansung 17579, Korea ]
• Seung-Hee Choi [ Department of Animal Biotechnology, Graduate School of Hankyong National University, Ansung 17579, Korea ]
• Hyo-Eun Joo [ Department of Animal Life Science, Hankyong National University, Ansung 17579, Korea ]
• Sang-Gwon Kim [ Department of Animal Life Science, Hankyong National University, Ansung 17579, Korea ]
• Yean-Ji Kim [ Department of Animal Life Science, Hankyong National University, Ansung 17579, Korea ]
• Gyeong-Eun Park [ Department of Animal Life Science, Hankyong National University, Ansung 17579, Korea ]

참고문헌

발행기관

간행물

관심저널 등록

• 간행물명

  Journal of Animal Reproduction and Biotechnology

• 간기

  계간

• pISSN

  2671-4639

• eISSN

  2671-4663

• 수록기간

  2019~2026

• 십진분류

  KDC 527 DDC 636