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초록

Antiplaque and antigingivitic activity of an oral rinse containing cetylpyridinium chloride - A randomized clinical trial

첫 페이지 보기
  • 발행기관
    한국물학회 바로가기
  • 간행물
    한국물학회지 바로가기
  • 통권
    Vol.9 No.1 (2021.11)바로가기
  • 페이지
    pp.40-40
  • 저자
    Jayson Antonio, Md. Habibur Rahman, Cheol-Su Kim, Kyu-Jae Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A403241

원문정보

초록

영어
Poor oral hygiene has been linked to microbiome-related systemic infections such as cardiovascular disease, type 2 diabetes, cancer, and dementia, so maintaining good oral hygiene becomes an essential part of overall health. The objective of this study was to examine the efficacy of OR containing 0.045% cetylpyridinium chloride (CPC) on oral-health related parameters through a 6-wk double-blinded and randomized clinical trial. At baseline, 80 subjects were assigned into 2 groups: Control (Con) group treated with oral rinse without active ingredient (n=40), and Experimental (Exp) group treated with oral rinse containing CPC (n=40), and received teeth scaling before clinical treatment. The subjects gargled using 20 mL of oral rinse for 30 s after brushing their teeth twice a day for 4 wk. The results demonstrated a substantial decrease in odor causing volatile sulfur compounds (hydrogen sulfide and methyl mercaptan) in the Exp compared to Con. Furthermore, the Exp group dramatically reduced oral bacteria (p < 0.05), lessened tongue coating index (TCI) (p < 0.05), and improved periodontal and gingival health faster than Con group. Collectively, application of CPC-containing oral rinse showed positive effect for oral health condition by improving mouth odor, TCI and oral bacteria, and might be recommended as an adjunctive to the standard home care routine for people with gingivitis.

키워드

oral hygiene cetylpyridinium chloride anti-plaque anti-gingivitic oral rinse clinical trial

저자

  • Jayson Antonio [ Department of Microbiology ]
  • Md. Habibur Rahman [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, South Korea. Department of Global Medical Science, Yonsei University Graduate School, Wonju 26426, Gangwon-do, South Korea ]
  • Cheol-Su Kim [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, South Korea. ]
  • Kyu-Jae Lee [ Department of Environmental Medical Biology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, South Korea. ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국물학회 [The Korean Water Society]
  • 설립연도
    2010
  • 분야
    자연과학>생물학
  • 소개
    기능수관련연구 경영과 정보를 공유, 일본 중국기능수재단 협회전문가 초빙하여 학회와의 정보교류 기능수관련 학회 및 학술지를 발행하여 물관련연구정보교류에 목적을 두고 있음.

간행물

  • 간행물명
    한국물학회지 [Korean Journal of Waters]
  • 간기
    부정기
  • pISSN
    2233-4653
  • 수록기간
    2010~2021
  • 십진분류
    KDC 539 DDC 628

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