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Original Article

국내 성인환자에서 죽상동맥경화성 심혈관질환 위험도와 스타틴 처방 현황
Atherosclerotic Cardiovascular Disease Risk and Statin Prescription Status in Korean Adult Patients

첫 페이지 보기
  • 발행기관
    한국임상약학회 바로가기
  • 간행물
    한국임상약학회지 KCI 등재 바로가기
  • 통권
    제31권 제3호 (2021.09)바로가기
  • 페이지
    pp.198-204
  • 저자
    김종윤, 유기연
  • 언어
    한국어(KOR)
  • URL
    https://www.earticle.net/Article/A401442

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원문정보

초록

영어
Background: Cardiovascular (CV) disease is known as one of the major causes of death from disease worldwide. Statin therapy plays a pivotal role in atherosclerotic cardiovascular disease (ASCVD) lowering the LDL-cholesterol level effectively. The purpose of this study was to evaluate the association of the intensity of statin therapy in adult patients of Korea and the risk of ASCVD of the patient group. Methods: We used data from sample of patients from the Health Insurance Review and Assessment Service (HIRA-NPS- 2018). We analyzed the patterns of prescribing statins including types of statin, statin intensity, and number of patients with ASCVD or risk of ASCVD. Results: 155,512 patients were included in the analysis, and 27,950 patients (18.0%) was over 75 years. Highintensity statin usage was increased in ASCVD patients compared with the low-intensity statin use. The OR (odds ratio) of highintensity statin were increased in myocardial infarction patients compared with low-intensity statin use showing the highest OR; 12.40 (95% CI; 9.48-16.22). At patient groups of angina, ischemic heart disease and carotid disease, high-intensity statin prescription rate was increased compared with low-intensity statin. However, there was no statistical significance between both statin prescription rates in patients of peripheral arterial disease, abdominal aneurysm, diabetic mellitus and atherosclerosis. Conclusion: The statin prescription rate showed intensity increasing tendency according to the risk of ASCVD. More aggressive statin therapy might be beneficial for the ASCVD patients based on the recent guidelines of dyslipidemia.

목차

ABSTRACT
연구 방법
분석 자료 및 대상 환자
스타틴 강도 분류 기준
ASCVD 위험도 분류 기준
통계분석
연구 결과
대상 환자 특성
스타틴 사용 분석
심혈관계 질환 발생 위험도에 따른 스타틴 사용 분석
ASCVD 및 ASCVD 위험도와 처방된 스타틴 강도 연관성
고찰 및 결론
참고문헌

키워드

Statin intensity dyslipidemia ASCVD atherosclerotic cardiovascular disease

저자

  • 김종윤 [ Jong Yoon Kim | 동덕여자대학교 약학대학 ]
  • 유기연 [ Kiyon Rhew | 동덕여자대학교 약학대학 ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국임상약학회 [Korean College of Clinical Pharmacy]
  • 설립연도
    1
  • 분야
    의약학>약학
  • 소개
    합리적 약물치료(rational pharmacotherapy)의 보장 및 증진을 궁극목적으로 하며 이를 달성하기 위해 임상약학의 발전과 회원 상호간의 친목을 도모한다.

간행물

  • 간행물명
    한국임상약학회지 [Korean Journal of Clinical Pharmacy]
  • 간기
    계간
  • pISSN
    1226-6051
  • 수록기간
    1991~2026
  • 등재여부
    KCI 등재
  • 십진분류
    KDC 518 DDC 615

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